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Supelco

Dragendorff reagent

for TLC derivatization

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About This Item

CAS Number:
39775-75-2
MDL number:
MFCD00283106
UNSPSC Code:
12000000
NACRES:
NA.22

grade

for TLC derivatization

Quality Level

100

composition

acetic acid
ethyl acetate
sodium iodide
sodium tetraiodobismutate

technique(s)

thin layer chromatography (TLC): suitable

InChI

1S/Bi.4HI.K/h;4*1H;/q+3;;;;;+1/p-4

InChI key

ONBIUAZBGHXJDM-UHFFFAOYSA-J

Application


  • Nematocidal alkaloids from the roots of Stemona mairei: This study explores the use of Dragendorff reagent for the identification of nematocidal alkaloids, demonstrating its critical role in the pharmacological profiling and characterization of natural products (Shi et al., 2023).

  • Rapid Detection and Determination of Scopolamine in Black Henbane: Leveraging Dragendorff reagent, this research developed a novel nanosensor for detecting scopolamine, an important application in pharmaceutical analysis and toxicology (Mousavizadeh et al., 2022).

  • Proximate analysis and multi spectrometric analysis of Strychnos nux-vomica nuts: The use of Dragendorff reagent in the multi-spectrometric analysis highlights its versatility in chemical synthesis and compound identification, providing essential insights for medicinal chemistry (Ramachandran et al., 2022).

  • TLC-MS identification of alkaloids in Leonuri Herba and Leonuri Fructus: This study used Dragendorff reagent to optimize a universal derivatization method, enhancing the detection and analysis of key pharmaceutical compounds in traditional medicine (Zhang et al., 2021).

  • Densitometric TLC analysis for control of tropane and steroidal alkaloids in Lycium barbarum: Demonstrates the application of Dragendorff reagent in food chemistry for ensuring the safety and efficacy of herbal supplements through the precise detection of alkaloids (Kokotkiewicz et al., 2017).

Other Notes

This non-aqueous Thiess, Reuther and Vagujfalvi variant of the reagent is used to detect alkaloids and other nitrogen compounds in TLC

Signal Word

Danger

Hazard Statements

H225 - H314 - H336

Hazard Classifications

Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B - STOT SE 3

Target Organs

Central nervous system

Storage Class Code

3 - Flammable liquids

WGK

WGK 3

Flash Point(F)

44.6 °F

Flash Point(C)

7 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCJ6510
BCBX4809
BCBM2462V
BCBL2920V
BCBL2919V

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Feng Qiu et al.
Drug metabolism and disposition: the biological fate of chemicals, 36(11), 2159-2165 (2008-08-16)
The urinary metabolites of berberine, an isoquinoline alkaloid isolated from several Chinese herbal medicines, were investigated in rats and humans. Using macroporous adsorption resin chromatography, open octadecyl silane column chromatography and preparative high-performance liquid chromatography, we isolated seven metabolites (HM1-HM7)
E. Talas et al.
J. Planar Chromatogr., 5, 28-28 (1992)
W. Funk et al.
J. Planar Chromatogr., 4, 123-123 (1991)
Effect of Annona muricata, Abutilon indicum and Evolvulus alsinoides extract on spore germination of sorghum grain mold fungi.
Basha, S. Ameer, A. Sajeli Begum, and G. Raghavendra
International Journal of Bio-resource and Stress Management, 5.1, 102-106 (2014)
A. Baerheim Svendsen
J. Planar Chromatogr., 2, 8-8 (1989)
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