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W261513

Sigma-Aldrich

Lauric aldehyde

greener alternative

natural, ≥95%, FG

Synonym(s):

Dodecyl aldehyde, Aldehyde C12, Dodecanal, Lauraldehyde, Laurinaldehyde

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About This Item

Linear Formula:
CH3(CH2)10CHO
CAS Number:
Molecular Weight:
184.32
FEMA Number:
2615
Beilstein:
1703917
EC Number:
Council of Europe no.:
99c
MDL number:
UNSPSC Code:
12164502
PubChem Substance ID:
Flavis number:
5.011
NACRES:
NA.21

grade

FG
Fragrance grade
Halal
Kosher
natural

Quality Level

Agency

follows IFRA guidelines
meets purity specifications of JECFA

reg. compliance

EU Regulation 1223/2009
EU Regulation 1334/2008 & 178/2002
FDA 21 CFR 117
FDA 21 CFR 172.515

Assay

≥95%

greener alternative product characteristics

Less Hazardous Chemical Syntheses
Use of Renewable Feedstocks
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

refractive index

n20/D 1.435 (lit.)

bp

185 °C/100 mmHg (lit.)

density

0.831 g/mL at 25 °C (lit.)

application(s)

flavors and fragrances

Documentation

see Safety & Documentation for available documents

food allergen

no known allergens

fragrance allergen

no known allergens

greener alternative category

Organoleptic

green; floral; citrus; waxy; soapy

SMILES string

CCCCCCCCCCCC=O

InChI

1S/C12H24O/c1-2-3-4-5-6-7-8-9-10-11-12-13/h12H,2-11H2,1H3

InChI key

HFJRKMMYBMWEAD-UHFFFAOYSA-N

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General description

Lauric aldehyde is one of the main aliphatic green volatile compounds in macerated grape cluster stems. It is also one of the key flavor constituents of grapefruit oil.

Application


  • Utility of ToxTracker in animal alternative testing strategy for fragrance materials.: This study highlights the use of ToxTracker, a suite of reporter cell lines, to evaluate the genetic toxicity of fragrance materials, including lauric aldehyde, offering a potential alternative to animal testing and advancing the safety assessment of consumer products (Thakkar et al., 2023).

  • In vitro evaluation of polymeric micelles based on hydrophobically-modified sulfated chitosan as a carrier of doxorubicin.: Research demonstrates the potential of hydrophobically-modified sulfated chitosan micelles, incorporating lauric aldehyde, for improving the delivery of chemotherapeutic agents, particularly doxorubicin, enhancing drug stability and reducing side effects (Wang et al., 2012).

  • Biocompatibility of injectable chitosan-phospholipid implant systems.: Investigates the biocompatibility of chitosan-phospholipid injectable implants, where lauric aldehyde could play a role in modifying polymer matrices to enhance biocompatibility and drug release profiles, critical for medical implant technologies (De Souza et al., 2009).


Pictograms

Exclamation markEnvironment

Signal Word

Warning

Hazard Statements

Hazard Classifications

Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

213.8 °F - closed cup

Flash Point(C)

101 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Genotoxicity of flavor and fragrance materials was assessed in Turkey Egg Genotoxicity Assay (TEGA) using 32P-nucleotide postlabeling (NPL) and comet assays to detect hepatic DNA adducts and strand breaks. Twenty materials having results in GADD45a-Gluc 'BlueScreen HC' genotoxicity assay, and
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Journal of pharmaceutical sciences, 104(3), 1187-1196 (2015-01-13)
The objective of this study is to develop and compare several Sorafenib-loaded biocompatible nanoparticle models in order to optimize drug delivery and tumor cellular kill thereby improving the quality of Sorafenib-regimented chemotherapy. Sorafenib-loaded poly (lactic-co-glycolic) acid (PLGA), 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) liposomes

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