37347

O-(2-Oxo-1(2H)pyridyl)-N,N,N′,N′-tetramethyluronium tetrafluoroborate

≥99.0% (HPLC)

• Synonym(s): O-(1,2-Dihydro-2-oxo-1-pyridyl)-N,N,N′-N′-tetramethyluronium tetrafluoroborate, TPTU
• Empirical Formula (Hill Notation): C₁₀H₁₆BF₄N₃O₂
• CAS Number: 125700-71-2
• Molecular Weight: 297.06
• MDL number: MFCD00075475
• UNSPSC Code: 12352005
• PubChem Substance ID: 57649720
• NACRES: NA.22

Properties

• Quality Level: 100
• Assay: ≥99.0% (HPLC)
• reaction suitability: reaction type: Coupling Reactions
• mp: 140 °C (dec.) (lit.)
• application(s): peptide synthesis
• storage temp.: 2-8°C
• SMILES string: F[B-](F)(F)F.CN(C)C(\ON1C=CC=CC1=O)=[N+](/C)C
• InChI: 1S/C10H16N3O2.BF4/c1-11(2)10(12(3)4)15-13-8-6-5-7-9(13)14;2-1(3,4)5/h5-8H,1-4H3;/q+1;-1
• InChI key: CZQGINAUZYECAI-UHFFFAOYSA-N

Description

Application

Reagent for:
Amidation
Peptide Coupling
Esterification of nucleosides to solid phase supports for oligonucleoside synthesis

Other Notes

Coupling reagent for peptide synthesis, especially suited for segment condensation with little racemization

Safety Information

• Pictograms: GHS05,GHS07
• Signal Word: Danger
• Hazard Statements: H317,H318
• Precautionary Statements: P261 - P272 - P280 - P302 + P352 - P305 + P351 + P338 - P333 + P313
• Hazard Classifications: Eye Dam. 1 - Skin Sens. 1A
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves