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Key Documents

287288

Sigma-Aldrich

3-(2-Thienyl)-DL-alanine

≥98%

Synonym(s):

2-Amino-3-(2-thienyl)propionic acid

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About This Item

Empirical Formula (Hill Notation):
C7H9NO2S
CAS Number:
Molecular Weight:
171.22
Beilstein:
82874
EC Number:
MDL number:
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.22

Assay

≥98%

form

powder

reaction suitability

reaction type: solution phase peptide synthesis

mp

275-277 °C (dec.) (lit.)

application(s)

peptide synthesis

SMILES string

NC(Cc1cccs1)C(O)=O

InChI

1S/C7H9NO2S/c8-6(7(9)10)4-5-2-1-3-11-5/h1-3,6H,4,8H2,(H,9,10)

InChI key

WTOFYLAWDLQMBZ-UHFFFAOYSA-N

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Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Uptake and incorporation of amino acids by suspension cultured mammalian cells: a comparative study involving eleven naturally-occurring and four analogue amino acids.
D N Wheatley et al.
Cytobios, 30(118), 101-126 (1981-01-01)
D P Bedard et al.
Journal of bacteriology, 141(1), 100-105 (1980-01-01)
When treated with the amino acid analog beta-2-DL-thienylalanine, cells of the yeast Saccharomyces cerevisiae accumulated in the G1 portion of the cell cycle at the "start" event. This G1 arrest was accompanied by a rapid decrease in the rate of
G Riccardi et al.
Journal of bacteriology, 147(3), 1002-1007 (1981-09-01)
Mutants of Spirulina platensis resistant to 5-fluorotryptophan, beta-3-thienyl-alanine, ethionine, p-fluorophenylalanine, or azetidine-2-carboxylic acid were isolated. Some of these mutants appeared to be resistant to more than one analog and to overproduce the corresponding amino acids. A second group was composed
"Physiological phenylketonuria": a biochemical defect caused by delayed maturation of the phenylalanine hydroxylation pathway and by competition with the phenylalanine biosynthetic pathway.
K J Brown
Medical hypotheses, 6(2), 215-224 (1980-02-01)
K J Brown et al.
Antonie van Leeuwenhoek, 45(4), 531-546 (1979-01-01)
Mice fed beta-2-thienylalanine (beta-2-T) by oesophageal tube were no more susceptible to gastrointestinal tract colonization by Salmonella typhimurium or Shigella flexneri III than control mice fed water. In both beta-2-T-fed and water-fed groups, the increasing dosage of S. typhimurium, in

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