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240230

Sigma-Aldrich

Phthalimide

≥99%

Synonym(s):

1,3-Dihydro-1,3-dioxoisoindole

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About This Item

Empirical Formula (Hill Notation):
C8H5NO2
CAS Number:
85-41-6
Molecular Weight:
147.13
Beilstein:
118522
EC Number:
201-603-3
MDL number:
MFCD00005881
UNSPSC Code:
12352100
PubChem Substance ID:
24854410
NACRES:
NA.22

Assay

≥99%

mp

232-235 °C (lit.)

solubility

water: slightly soluble(lit.)

SMILES string

O=C1NC(=O)c2ccccc12

InChI

1S/C8H5NO2/c10-7-5-3-1-2-4-6(5)8(11)9-7/h1-4H,(H,9,10,11)

InChI key

XKJCHHZQLQNZHY-UHFFFAOYSA-N

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Application

Phthalimide was used in the synthesis of 6-amino agarose (AA) by Mitsunobu-inspired microwave mediated method.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 1

Flash Point(F)

302.0 °F - closed cup

Flash Point(C)

150 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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N-(4-Bromobutyl)phthalimide 98%

Sigma-Aldrich

100919

N-(4-Bromobutyl)phthalimide

Alessio Pierini et al.
Journal of veterinary science, 21(5), e60-e60 (2020-10-06)
Tumor-associated neoangiogenesis is a crucial target for antitumor therapies. Thalidomide (TAL) is a promising anti-neoangiogenetic drug that has recently been used in the treatment of several malignancies in dogs. The aim of the study was to assess the pharmacokinetics of
Stalin Kondaveeti et al.
Carbohydrate polymers, 106, 365-373 (2014-04-12)
A facile 6-aminoagarose (AA) mediated synthesis of new fluorogenic amides of agarose with nicotinic (AA-NA) and picolinic acids (AA-PA) employing carbodiimide chemistry have been described. 6-Amino agarose (AA) was synthesized in a facile Mitsunobu-inspired microwave mediated method involving the reaction
Ive Hermans et al.
Physical chemistry chemical physics : PCCP, 10(8), 1125-1132 (2008-02-14)
Abstraction of hydrogen atoms by pthalimide-N-oxyl radicals is an important step in the N-hydroxyphthalimide catalyzed autoxidation of hydrocarbons. In this contribution, the temperature dependency of this reaction is evaluated by a detailed transition state theory based kinetic analysis for the
Jean L Santos et al.
Bioorganic & medicinal chemistry, 17(11), 3795-3799 (2009-05-12)
New phthalimide derivatives were easily prepared through condensation of phthalic anhydride and selected amines with variable yields (70-90%). All compounds (3a-l) were evaluated against Mycobacterium tuberculosis H(37)Rv using Alamar Blue susceptibility. The compounds 3c, 3i, and 3l have the minimum
Clarina I Manley-King et al.
Bioorganic & medicinal chemistry, 19(16), 4829-4840 (2011-07-23)
Literature reports that isatin as well as C5- and C6-substituted isatin analogues are reversible inhibitors of human monoamine oxidase (MAO) A and B. In general, C5- and C6-substitution of isatin leads to enhanced binding affinity to both MAO isozymes compared
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