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Prostaglandin A₁

Name: Prostaglandin A<SUB>1</SUB>
Brand: SIGMA

≥98% (HPLC), powder, NF-κB inhibitor

Synonym(s):

(13E,15S)-15-Hydroxy-9-oxoprosta-10,13-dien-1-oic acid, PGA₁

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About This Item

Empirical Formula (Hill Notation):

C₂₀H₃₂O₄

CAS Number:

14152-28-4

Molecular Weight:

336.47

NACRES:

NA.77

PubChem Substance ID:

24898834

UNSPSC Code:

12352211

MDL number:

MFCD00077858

Beilstein/REAXYS Number:

2003401

Assay:

≥98%

Form:

powder

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Properties

Product Name

Prostaglandin A₁, synthetic

biological source

synthetic

Quality Segment

200

assay

≥98%

form

powder

storage temp.

−20°C

SMILES string

O=C1[C@H](CCCCCCC(O)=O)[C@@H](/C=C/[C@H](CCCCC)O)C=C1

InChI

1S/C20H32O4/c1-2-3-6-9-17(21)14-12-16-13-15-19(22)18(16)10-7-4-5-8-11-20(23)24/h12-18,21H,2-11H2,1H3,(H,23,24)/b14-12+/t16-,17-,18+/m0/s1

InChI key

BGKHCLZFGPIKKU-LDDQNKHRSA-N

Description

Biochem/physiol Actions

Prostaglandin A1 (PGA1) is a cyclopentenone prostaglandin containing chemically reactive α,β-unsaturated carbonyl. This cyclooxygenase 2 (COX-2) metabolic product aids in regulating the development and progression of Alzheimer′s disease (AD). In addition, PGA1 also regulates various biological processes via Michael addition. It exhibits antiviral activity against avian influenza A viruses (IAV) by inducing cytoprotective heat shock response in infected cells and by inhibiting nuclear factor-κB (NF-κB) activity.

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1 of 1

This Item	1578500	P7527	900100P
Sigma-Aldrich P7265 Prostaglandin A₁	USP 1578500 Prostaglandin A₁	Sigma-Aldrich P7527 Prostaglandin E₁	Avanti 900100P PGE1
form powder	form -	form powder	form powder
assay ≥98%	assay -	assay ≥60% (HPLC)	assay >99% (TLC)
Quality Level 200	Quality Level -	Quality Level 200	Quality Level -
storage temp. −20°C	storage temp. −20°C	storage temp. −20°C	storage temp. −20°C
biological source synthetic	biological source -	biological source synthetic (organic)	biological source -

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Explore all of our products under Prostaglandin A₁

pictograms

GHS08,GHS07

signalword

Danger

hcodes

H302,H360F

pcodes

P201 - P301 + P312 + P330 - P308 + P313

Hazard Classifications

Acute Tox. 4 Oral - Repr. 1B

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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