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D1925

Demecolcine solution

10 μg/mL in HBSS, ACF Qualified, BioXtra

Synonym(s):

Colcemid™ solution, N-Deacetyl-N-methylcolchicine solution

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About This Item

CAS Number:
477-30-5
NACRES:
NA.75
PubChem Substance ID:
24893569
UNSPSC Code:
12352207
MDL number:
MFCD00075459
Form:
liquid
Quality level:
400
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Quality Level

400

sterility

sterile-filtered

product line

BioXtra

form

liquid

concentration

10 μg/mL in HBSS

technique(s)

cell culture | mammalian: suitable

storage temp.

2-8°C

SMILES string

CN[C@H]1CCc2cc(OC)c(OC)c(OC)c2C3=CC=C(OC)C(=O)C=C13

InChI

1S/C21H25NO5/c1-22-15-8-6-12-10-18(25-3)20(26-4)21(27-5)19(12)13-7-9-17(24-2)16(23)11-14(13)15/h7,9-11,15,22H,6,8H2,1-5H3/t15-/m0/s1

InChI key

NNJPGOLRFBJNIW-HNNXBMFYSA-N

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This Item
10295892001P4707P4832
Demecolcine solution 10 μg/mL in HBSS, ACF Qualified, BioXtra

Sigma-Aldrich

D1925

Demecolcine solution

Colcemid solution, suitable for blocking, sterile; 0.2 μm filtered

Roche

10295892001

Colcemid

Poly-L-lysine solution 0.01%, sterile-filtered, BioReagent, suitable for cell culture

Sigma-Aldrich

P4707

Poly-L-lysine solution

Poly-L-lysine solution mol wt 150,000-300,000, 0.01%, sterile-filtered, BioReagent, suitable for cell culture

Sigma-Aldrich

P4832

Poly-L-lysine solution

form

liquid

form

solution

form

liquid

form

solution

technique(s)

cell culture | mammalian: suitable

technique(s)

blocking: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

Quality Level

400

Quality Level

100

Quality Level

300

Quality Level

200

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

sterility

sterile-filtered

sterility

sterile; 0.2 μm filtered

sterility

sterile-filtered

sterility

sterile-filtered

product line

BioXtra

product line

-

product line

BioReagent

product line

BioReagent

Application

Used for cell synchronization by arresting them at metaphase. Qualified for use in animal component free applications.

Legal Information

Colcemid is a trademark of Ciba-Geigy Corporation

Storage Class

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

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Certificates of Analysis (COA)

Lot/Batch Number
RNBL4894
RNBK5602
RNBJ8018
RNBJ4035
RNBJ1156

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Vandana Relan et al.
PloS one, 8(3), e58132-e58132 (2013-03-22)
Malignant mesothelioma is an aggressive tumour of serosal surfaces most commonly pleura. Characterised cell lines represent a valuable tool to study the biology of mesothelioma. The aim of this study was to develop and biologically characterise six malignant mesothelioma cell
Ting-Yuan Tseng et al.
Molecules (Basel, Switzerland), 25(18) (2020-09-11)
Identification of the existence of G-quadruplex (G4) structure, from a specific G-rich sequence in cells, is critical to the studies of structural biology and drug development. Accumulating evidence supports the existence of G4 structure in vivo. Particularly, time-gated fluorescence lifetime
Dimitris Ioannou et al.
Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology, 17(4), 519-530 (2009-08-01)
In the field of nanotechnology, quantum dots (QDs) are a novel class of inorganic fluorochromes composed of nanometre-scale crystals made of a semiconductor material. Given the remarkable optical properties that they possess, they have been proposed as an ideal material
Peter Burkovics et al.
Nucleic acids research, 44(7), 3176-3189 (2016-01-23)
Successful and accurate completion of the replication of damage-containing DNA requires mainly recombination and RAD18-dependent DNA damage tolerance pathways. RAD18 governs at least two distinct mechanisms: translesion synthesis (TLS) and template switching (TS)-dependent pathways. Whereas TS is mainly error-free, TLS
Hailing Yang et al.
The Journal of biological chemistry, 285(42), 32242-32250 (2010-08-11)
Drugs that target microtubules are thought to inhibit cell division and cell migration by suppressing dynamic instability, a "search and capture" behavior that allows microtubules to probe their environment. Here, we report that subtoxic drug concentrations are sufficient to inhibit
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Global Trade Item Number

SKUGTIN
D1925-20ML04061833561072
D1925-100ML04061838259271

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