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Key Documents

A3830

Sigma-Aldrich

Adrenomedullin rat

≥95% (HPLC)

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About This Item

Empirical Formula (Hill Notation):
C242H379N77O75S5
CAS Number:
Molecular Weight:
5727.39
MDL number:
UNSPSC Code:
51111800
NACRES:
NA.32

Quality Level

Assay

≥95% (HPLC)

form

powder

UniProt accession no.

storage temp.

−20°C

Gene Information

rat ... Adm(25026)

Amino Acid Sequence

Tyr-Arg-Gln-Ser-Met-Asn-Gln-Gly-Ser-Arg-Ser-Thr-Gly-Cys-Arg-Phe-Gly-Thr-Cys-Thr-Met-Gln-Lys-leu-Ala-His-Gln-Ile-Tyr-Gln-Phe-Thr-Asp-Lys-Asp-Lys-Asp-Gly-Met-Ala-Pro-Arg-Asn-Lys-Ile-Ser-Pro-Gln-Gly-Tyr-NH2

Biochem/physiol Actions

Elicits a potent and long-lasting hypotensive activity in anesthetized rats. Plays a key role in regulating endometrial angiogenesis.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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V Kesik et al.
Clinical and experimental dermatology, 35(8), 897-901 (2010-03-30)
Extravasation of vesicant drugs such as vinca alkaloids causes severe injury, which may range from erythema to skin necrosis or ulceration. The skin necrosis may not be fully evident until several weeks or months after the initial damage, and may

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