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Key Documents

A3133

Sigma-Aldrich

Nα-Acetyl-L-arginine

≥98% (TLC), suitable for deacetylase assays

Synonym(s):

N2-acetyl-L-alanine

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About This Item

Empirical Formula (Hill Notation):
C8H16N4O3
CAS Number:
Molecular Weight:
216.24
EC Number:
MDL number:
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.26

Product Name

Nα-Acetyl-L-arginine,

Assay

≥98% (TLC)

Quality Level

form

powder

technique(s)

deacetylase assay: suitable

color

colorless to white

storage temp.

−20°C

SMILES string

NC(NCCC[C@H](NC(C)=O)C(O)=O)=N

InChI

1S/C8H16N4O3/c1-5(13)12-6(7(14)15)3-2-4-11-8(9)10/h6H,2-4H2,1H3,(H,12,13)(H,14,15)(H4,9,10,11)/t6-/m0/s1

InChI key

SNEIUMQYRCDYCH-LURJTMIESA-N

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Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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T W Lo et al.
The Journal of biological chemistry, 269(51), 32299-32305 (1994-12-23)
The physiological alpha-oxoaldehyde methylglyoxal binds and modifies arginine, lysine, and cysteine residues in proteins. The kinetics and mechanism of these reactions were investigated with N alpha-acetylamino acids and bovine serum albumin at pH 7.4 and 37 degrees C. The reaction
Daniela Balz et al.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 21(2), 75-82 (2003-03-05)
Tissue accumulation of arginine (Arg), N-acetylarginine (NA), argininic acid (AA) and homoarginine (HA) occurs in hyperargininemia, an inborn error of the urea cycle. In the present study, we investigated the in vitro effects of Arg, NA, AA and HA on
Pojjana Charurin et al.
Journal of agricultural and food chemistry, 50(13), 3751-3756 (2002-06-13)
Coffee model systems prepared from combinations of chlorogenic acid (CGA), N(alpha)-acetyl-1-arginine (A), sucrose (S), and cellulose (C) were roasted at 240 degrees C for 4 min prior to analysis by UV-visible spectrophotometry, capillary zone electrophoresis (CZE), and the ABTS radical
Z Zhang et al.
Nature structural biology, 7(2), 127-133 (2000-02-03)
Clavaminate synthase (CAS), a remarkable Fe(II)/2-oxoglutarate oxygenase, catalyzes three separate oxidative reactions in the biosynthesis of clavulanic acid, a clinically used inhibitor of serine beta-lactamases. The first CAS-catalyzed step (hydroxylation) is separated from the latter two (oxidative cyclization/desaturation) by the
James M Mathews et al.
Journal of agricultural and food chemistry, 58(24), 12761-12768 (2010-11-17)
The butter flavorant diacetyl (2,3-butanedione) is implicated in causing obliterative bronchiolitis in microwave popcorn plant workers. Because diacetyl modifies arginine residues, an immunological basis for its toxicity is under investigation. Reaction products of diacetyl with N-α-acetylarginine (AcArg) were determined as

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