76258

Paraplast Plus^®

suitable for electron microscopy, pellets (fast-melting)

• Synonym(s): Paraplast Plus^® embedding media, Paraffin – polyisobutylene mixture
• CAS Number: 125387-89-5
• UNSPSC Code: 12171500
• EC Number: 232-315-6
• NACRES: NA.47
• MDL number: MFCD00131795

Properties

• form: pellets (fast-melting)
• Quality Segment: 100
• technique(s): electron microscopy: suitable
• thickness: ≤1 μm , short ribbons, ≤2 μm , sectioning: continuous ribbons
• mp: 56-57 °C
• application(s): hematology; histology
• storage temp.: 2-8°C

Description

General description

Paraplast Plus^® is a refined mixture of highly purified paraffin containing complex elastomer of regulated molecular weights plus a small percentage of dimethyl sulfoxide (DMSO) for fast tissue penetration. It produces minimal tissue compression and wrinkle-free sections and cuts to 4 μm thickness with excellent ribbon continuity.
Paraplast^® tissue embedding media are made from highly purified wax combined with plastic polymers for tensile strength and elasticity. Paraplast Plus^® provides rapid infiltration during processing as well as great compression resistance during sectioning for preserved morphology and thin, distortion-free sections.
Our range of Paraplast products improve the elasticity of brittle, difficult-to-cut tissues making it easier to produce excellent, wrinkle-free sections.

Application

Paraffin polyisobutylene mixture is a tissue embedding medium composed of highly purified paraffin and polyisobutylene and a low level of dimethyl sulfoxide (DMSO) to enhance the rate of tissue penetration. Paraffin-polyisobutylene (76258) supports thin wrinkle-free sectioning down to 4 microM with more flexible and continuous ribbons.

Recommended for large specimens and tissue that commonly presents infiltration problems.

Features and Benefits

• Produces minimal tissue compression and wrinkle-free sections, and cuts to 4 μm thickness with excellent ribbon continuity.
• 0.8% DMSO enhances ease of infiltration and sectioning for tissues difficult to process with regular Paraplast.
• Higher melt viscosity and lower permeability to water vapor creates better adhesion and a more pliable, flexible film.
• Optimal infiltration and embedding for high-quality sections.
• Great compression resistance and ribbon continuity.
• Remarkable morphology preservation and distortion-free sections.

Legal Information

Paraplast is a registered trademark of Leica Biosystems

Paraplast Plus is a registered trademark of Leica Biosystems

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)