75903

Guanosine

≥97.0% (HPLC)

• Synonym(s): 9-(β-D-Ribofuranosyl)guanine, Guanine-9-β-D-ribofuranoside
• Empirical Formula (Hill Notation): C₁₀H₁₃N₅O₅
• CAS Number: 118-00-3
• Molecular Weight: 283.24
• NACRES: NA.51
• PubChem Substance ID: 329766751
• UNSPSC Code: 41106305
• EC Number: 204-227-8
• Beilstein/REAXYS Number: 625911

Properties

• Quality Segment: 200
• assay: ≥97.0% (HPLC)
• form: powder
• optical activity: [α]20/D -73±2°, c = 1.5% in 1 M NaOH
• impurities: ≤6.0% water
• mp: 250 °C (dec.) (lit.)
• SMILES string: [H]O[H].NC1=Nc2c(ncn2[C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)C(=O)N1
• InChI: 1S/C10H13N5O5/c11-10-13-7-4(8(19)14-10)12-2-15(7)9-6(18)5(17)3(1-16)20-9/h2-3,5-6,9,16-18H,1H2,(H3,11,13,14,19)/t3-,5-,6-,9-/m1/s1
• InChI key: NYHBQMYGNKIUIF-UUOKFMHZSA-N

Description

Application

Guanosine is a purine nucleoside that upon sequential phosphoylation (kinases) forms GTP which is used by RNA polymerases to synthesis RNA(s). GTP is also important in a wide range of GTPase-dependent cell signaling processes. Guanosine is used in selective matricies such a guanosine gels (G-gels) for use in capillary electrophoresis chiral selection and other applications.

Other Notes

Currently available only in Europe.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges