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About This Item
Empirical Formula (Hill Notation):
C7H5HgNaO3
CAS Number:
Molecular Weight:
360.69
UNSPSC Code:
12352103
NACRES:
NA.25
PubChem Substance ID:
EC Number:
205-340-5
Beilstein/REAXYS Number:
6118796
MDL number:
Assay:
≥95.0% (Hg)
Quality Level
assay
≥95.0% (Hg)
mp
≥300 °C
SMILES string
[Na+].O[Hg]c1ccc(cc1)C([O-])=O
InChI
1S/C7H5O2.Hg.Na.H2O/c8-7(9)6-4-2-1-3-5-6;;;/h2-5H,(H,8,9);;;1H2/q;2*+1;/p-2
InChI key
CBELQCYFTSHKPJ-UHFFFAOYSA-L
Application
4-(Hydroxymercuri)benzoic acid is an organic mercurial compound that reacts via mercury-sulfur affinity with sulfhydryl groups in peptides, proteins and other molecules. PCMB may be used for the determination of sulfhydryl groups in proteins according to Boyer, by atomic absorption, and stopped-flow measurements, G. Castronuovo-Lepore et al.. It may be used for specific applications such as probing the active site of an enzyme such as cytochrome C oxidase. 4-(Hydroxymercuri)benzoic acid appeared mistakenly as p-chloromercuriobenzoate [PCMB] in earlier literature.
Disclaimer
For U.S. Customers: Contains mercury; Do not place in trash - dispose according to local, state, or federal laws.


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Danger
Hazard Classifications
Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT RE 2
Storage Class
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
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Emilia Bramanti et al.
Clinical chemistry, 51(6), 1007-1013 (2005-04-23)
We developed a sensitive, specific method for the low-molecular-mass thiols cysteine, cysteinylglycine, glutathione, and homocysteine and validated the method for measurement of glutathione in blood. The technique was based on reversed-phase chromatography (RPC) coupled on line with cold vapor generation
G C Lepore et al.
European journal of biochemistry, 65(1), 171-176 (1976-05-17)
The reactivity of the sulfhydryl groups of histidyl-t RNA synthetase from Salmonella typhimurium and the effect of substrates on the reactivity has been studied using p-hydroxymercuribenzoate and 5, 5'-dithiobis (2-nitrobenzoic acid) as reagents. It has been found that 5, 5'-dithiobis
Daniel J Kutscher et al.
Analytical and bioanalytical chemistry, 401(9), 2691-2698 (2011-07-21)
A method was developed for the precise and accurate determination of ovalbumin labelled with p-hydroxy-mercuribenzoic acid (pHMB) using polyacrylamide gel electrophoresis with ns-laser ablation-inductively coupled plasma mass spectrometry. Following systematic optimisation of the ablation process in terms of detection sensitivity
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 55540-5G | 04061832582573 |
| 55540-25G | 04061832860374 |


