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Sigma-Aldrich

α-Carotene

≥95.0% (HPLC)

Synonym(s):

(+)-α-Carotene

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About This Item

Empirical Formula (Hill Notation):
C40H56
CAS Number:
7488-99-5
Molecular Weight:
536.87
Beilstein:
3227603
MDL number:
MFCD00136012
UNSPSC Code:
12352202
PubChem Substance ID:
329755985
NACRES:
NA.32

Assay

≥95.0% (HPLC)

form

powder

optical purity

enantiomeric excess: ≥95.0%

mp

183-185 °C

λ

2 % in methylene chloride (in hexane)

UV absorption

λ: 445-449 nm Amax

storage temp.

−20°C

SMILES string

CC(/C=C/[C@H]1C(C)=CCCC1(C)C)=C\C=C\C(C)=C\C=C\C=C(C)\C=C\C=C(\C=C\C2=C(C)CCCC2(C)C)C

InChI

1S/C40H56/c1-31(19-13-21-33(3)25-27-37-35(5)23-15-29-39(37,7)8)17-11-12-18-32(2)20-14-22-34(4)26-28-38-36(6)24-16-30-40(38,9)10/h11-14,17-23,25-28,37H,15-16,24,29-30H2,1-10H3/b12-11+,19-13+,20-14+,27-25+,28-26+,31-17+,32-18+,33-21+,34-22+/t37-/m0/s1

InChI key

ANVAOWXLWRTKGA-NTXLUARGSA-N

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General description

Carotenoids are natural products used in the food, animal feed, nutraceutical, and pharmaceutical industries. α-Carotene, a carotenoid with one β-ring and one ε-ring, is commonly present in the food. Orange carrots show a high concentration of α-carotene.

Application

α-Carotene may be used as a standard in high-performance liquid chromatography (HPLC) for carotenoid quantification in Corynebacterium glutamicum.

Biochem/physiol Actions

α-Carotene exhibits provitamin A activity. It can act as an efficient inhibitor than β-carotene on certain growth factors, like N-myc activity. α-Carotene serves as a good biomarker for fruit and vegetable consumption. High serum concentrations of α-carotene are associated with lower cardiovascular disease (CVD) mortality.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Overview of the Role of Antioxidant Vitamins as Protection Against Cardiovascular Disease: Implications for Aging
Aging null
Cheng Li et al.
Bioresource technology, 341, 125782-125782 (2021-08-23)
The carotenoid, α-carotene, is very beneficial for human health and wellness, but microbial production of this compound is notoriously difficult, due to the asymmetric rings on either end of its terpenoid backbone. Here, we report for the first time the
Li-En Yang et al.
Journal of integrative plant biology, 56(9), 902-915 (2014-06-20)
Carotene hydroxylases catalyze the hydroxylation of α- and β-carotene hydrocarbons into xanthophylls. In red algae, β-carotene is a ubiquitously distributed carotenoid, and hydroxylated carotenoids such as zeaxanthin and lutein are also found. However, no enzyme with carotene hydroxylase activity had
Vitamins
Clinical biochemistry of domestic animals null
Sebastiaan Bijttebier et al.
Journal of chromatography. A, 1332, 46-56 (2014-02-19)
Aim of study was to find the most suitable LC column for generic carotenoid screening. To represent the diversity of carotenoids in nature and to optimize chromatographic separation, a set of carotenoid standards was carefully chosen to account for the
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