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Lycopene

analytical standard

Synonym(s):

E160d, ψ,ψ-Carotene, 2,6,10,14,19,23,27,31-Octamethyl-dotriaconta-2,6,8,10,12,14,16,18,20,22,24,26,30-tridecaene

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About This Item

Empirical Formula (Hill Notation):
C40H56
CAS Number:
502-65-8
Molecular Weight:
536.87
EC Number:
207-949-1
MDL number:
MFCD00017350
UNSPSC Code:
85151701
PubChem Substance ID:
329766093
NACRES:
NA.24

grade

analytical standard

Quality Level

100

Assay

≥85.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

neat

shipped in

dry ice

storage temp.

-65 to -96°C

SMILES string

C\C(C)=C\CC\C(C)=C\C=C\C(C)=C\C=C\C(C)=C\C=C\C=C(C)\C=C\C=C(C)\C=C\C=C(/C)CC\C=C(\C)C

InChI

1S/C40H56/c1-33(2)19-13-23-37(7)27-17-31-39(9)29-15-25-35(5)21-11-12-22-36(6)26-16-30-40(10)32-18-28-38(8)24-14-20-34(3)4/h11-12,15-22,25-32H,13-14,23-24H2,1-10H3/b12-11+,25-15+,26-16+,31-17+,32-18+,35-21+,36-22+,37-27+,38-28+,39-29+,40-30+

InChI key

OAIJSZIZWZSQBC-GYZMGTAESA-N

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General description

Lycopene is a natural compound that belongs to the group of non-provitamin carotenoids and is responsible for the red color of tomatoes and other red-colored fruits and vegetables. It shows a stronger anti-oxidant activity compared to the other carotenoids.

Application

This analytical standard can also be used as follows:
  • Development of a Near-infrared spectroscopic (NIRS) technique for the quantitative analysis of lycopene in dehydrated tomato samples
  • Multi-residue analysis of thiamine, riboflavin, niacin, pyridoxine, folic acid, ascorbic acid, retinol, γ-tocopherol, phylloquinone, lycopene, and β-carotene in cherry tomato and pharmaceutical formulation samples using liquid chromatography (LC) combined with UV detection
  • Quantitative analysis of nine carotenoids in dietary supplement samples by an ultra-high performance supercritical fluid chromatography-photodiode array detection (UHPSFC-PDA) based method
  • Simultaneous determination of lycopene and ubidecarenone in their combined pharmaceutical dosage form by reversed phase-high performance liquid chromatography (RP-HPLC) coupled with UV detection at 400 nm, in accordance with International Conference on Harmonization ICH Q2 R guidelines
  • Raman spectroscopic analysis of orange-fleshed sweet potato samples to measure their carotenoid content
  • Simultaneous measurement of chlorophylls (a & b) and carotenoids (β-carotene and lycopene) in fruit samples of strawberry, apricot, and raspberry by two UV-vis spectrophotometric methods

Biochem/physiol Actions

Antioxidant micronutrient of tomatoes associated with decreased risk for cancer and cardiovascular disease. Enhances gap juction communication between cells via upregulation of connexin 43 and reduces proliferation of cancer cells in culture. Inhibits cholesterol synthesis and enhances low-density lipoprotein degradation.

Other Notes

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
BCCL6990
BCCJ9758
BCCL0854
BCCH7516
BCCG9652

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Sebastian Dams et al.
International journal of food sciences and nutrition, 71(6), 769-780 (2020-02-18)
The major aim of this controlled, randomised, open-labelled, parallel-grouped, clinical trial was to investigate whether supplementation with different dosages of omega-3 fatty acids (0.5 g/d and 1 g/d) from a plant-based fatty acid supplement affected omega-3-indices (O3I) in well-nourished, healthy people. In
Jinhyuk Kim et al.
Foods (Basel, Switzerland), 9(8) (2020-07-28)
The chemical stability of the lipophilic bioactives encapsulated in emulsions can be influenced by emulsion droplet interfacial characteristics as well as by the ability of antioxidants incorporated in emulsion to prevent the degradation of the encapsulated compounds. Therefore, this study
Jian Xu et al.
Molecular and cellular probes, 46, 101419-101419 (2019-07-08)
This study aims to investigate the influences of lycopene on ovarian cancer cells SKOV3 in vitro and the corresponding mechanism. SKOV3 cultures were divided into four groups and treated with lycopene at 0 (the control group), 1 × 10-6, 1 × 10-5 and 1 × 10-4 mol/L
April M Miguez et al.
Frontiers in microbiology, 9, 760-760 (2018-05-19)
Using cells as microbial factories enables highly specific production of chemicals with many advantages over chemical syntheses. A number of exciting new applications of this approach are in the area of precision metabolic engineering, which focuses on improving the specificity
Xiang-Dong Wang
The American journal of clinical nutrition, 96(5), 1214S-1222S (2012-10-12)
The beneficial effects of a high intake of tomatoes and tomato products on the risk of certain chronic diseases have been presented in many epidemiologic studies, with the suggestion that lycopene (a major carotenoid in tomatoes) is a micronutrient with
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