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Merck

MX1394

NMP

for Peptide Synthesis

Synonym(s):

1-Methyl-2-Pyrrolidone, 1-Methyl-2-pyrrolidinone,NMP

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About This Item

Linear Formula:
(CH3)-NC(=O)CH2CH2CH2-
CAS Number:
UNSPSC Code:
12352115
EC Index Number:
212-828-1
MDL number:
NACRES:
NA.21
Assay:
≥99.5% (GC)
Application(s):
peptide synthesis
Bp:
202 °C/1013 hPa
Vapor pressure:
0.32 hPa ( 20 °C)
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Product Name

1-Methyl-2-pyrrolidone, for Peptide Synthesis

SMILES string

N1(CCCC1=O)C

InChI

1S/C5H9NO/c1-6-4-2-3-5(6)7/h2-4H2,1H3

InChI key

SECXISVLQFMRJM-UHFFFAOYSA-N

vapor pressure

0.32 hPa ( 20 °C)

assay

≥99.5% (GC)

form

liquid

dilution

(for synthesis)

impurities

≤1 ppm Heavy metals (as Pb)
≤1.0 μeq/g Titrable base
≤300 ppm Water (H2O)
≤5 ppm Free amine (as dimethylamine)

color

clearAPHA: ≤20

pH

8.5-10.0 (20 °C, 100 g/L in H2O)

bp

202 °C/1013 hPa

mp

-24 °C

transition temp

flash point 91 °C

solubility

1000 g/L

density

1.03 g/cm3 at 20 °C

UV cutoff

≤275 nm

UV absorption

λ: 275 nm Amax: ≤1.00
λ: 280 nm Amax: ≤0.70
λ: 300 nm Amax: ≤0.30
λ: 350 nm Amax: ≤0.10
λ: 400 nm Amax: ≤0.01

application(s)

peptide synthesis

shipped in

ambient

storage temp.

room temp

Quality Level

Analysis Note

AppearanceClear, free from particulatesAssay (GC)99.5% minColor (APHA)20 maxFiltered through 0.2 µm filterTo pass testFormLiquidFree amine (as dimethylamine)5ppm maxHeavy metals (as Pb)1ppm maxResidue after ignition10ppm maxTitrable base1.0µeq/g maxUV Abs. at 275 nm1.00AU maxUV Abs. at 280 nm0.70AU maxUV Abs. at 300 nm0.30AU maxUV Abs. at 350 nm0.10AU maxUV Abs. at 400 nm0.01AU maxUV Cut-off275nm maxWater (H2O)300ppm max

Application

for Peptide Synthesis

Packaging

M-Bottle for Solvents
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Preparation Note

Product filtered through a 0.2 μm filter

pictograms

Health hazardExclamation mark

signalword

Danger

Hazard Classifications

Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 1

flash_point_f

195.8 °F - Pensky-Martens closed cup

flash_point_c

91 °C - Pensky-Martens closed cup


Certificates of Analysis (COA)

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