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561306

Sigma-Aldrich

P-Selectin, Human, Recombinant, CHO Cells

Synonym(s):

CD62P, GMP-140, LECAM-3, PADGEM

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About This Item

UNSPSC Code:
12352202
NACRES:
NA.75

recombinant

expressed in CHO cells

Quality Level

Assay

≥95% (SDS-PAGE)

form

lyophilized

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

impurities

<1.5 EU/μg Endotoxins (EU/μg of P-Selectin)

shipped in

wet ice

storage temp.

−20°C

General description

Recombinant, human P-selectin consisting of 730 amino acids minus the transmembrane and cytoplasmic domains expressed in CHO cells. This glycoprotein is expressed on activated platelets and endothelial cells. A specific interaction between P-selectin and P-selectin glycoprotein ligand-1, present on numerous cell types, promotes adhesion and acts along with L-selectin in establishing an initial interaction between circulating leukocytes and the endothelium.

Biochem/physiol Actions

Shown to bind to P-selectin ligands on U937 cells.

Warning

Toxicity: Standard Handling (A)

Physical form

Lyophilized from Dulbecco’s D-PBS (containing calcium and magnesium), 1% sorbitol.

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
Reconstitute at 1 mg/ml in sterile H₂O.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 2


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