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Key Documents

G4502

Sigma-Aldrich

Sodium glyoxylate monohydrate

≥93%

Synonym(s):

Glyoxylic acid sodium salt monohydrate, Oxoethanoic acid sodium salt

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About This Item

Linear Formula:
HC(O)COONa · H2O
CAS Number:
Molecular Weight:
114.03
Beilstein:
4003755
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

≥93%

storage temp.

−20°C

SMILES string

O.[Na+].[O-]C(=O)C=O

InChI

1S/C2H2O3.Na.H2O/c3-1-2(4)5;;/h1H,(H,4,5);;1H2/q;+1;/p-1

InChI key

VPWPWKBHCGJTTQ-UHFFFAOYSA-M

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General description

Sodium glyoxylate monohydrate, also known as Glyoxylic acid sodium salt monohydrate, is often utilized in the reductive amination of glyoxylate/pyruvate intermediates and ketoacids with hydroxylamine.

Application


  • Proteomic characterisation of polyethylene terephthalate and monomer degradation by Ideonella sakaiensis.: This paper details the degradation of polyethylene terephthalate and its monomers, highlighting the role of sodium glyoxylate monohydrate as a byproduct in biodegradable polymer production and its implications for environmental sustainability (Poulsen & Nielsen, 2023, Poulsen & Nielsen, 2023).

Sodium glyoxylate monohydrate is used as an intermediate in the transamination reaction in the formation of unstable keto esters during the synthesis of indolo [3,2-a] carbazoles.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Rossana Canavesi et al.
Journal of pharmaceutical and biomedical analysis, 173, 154-161 (2019-05-28)
In Anopheles gambiae, the most efficient vector of the malaria parasite Plasmodium falciparum, 3-hydroxykynurenine is endowed with a toxic potential. In adult mosquitoes, the excess of 3-hydroxykynurenine is removed by a specific transaminase (3-hydroxykynurenine transaminase, 3-HKT) which converts the compound
Chemistry and properties of indolocarbazoles
Tomasz J, et al.
Chemical Reviews, 118, 9058-9128 (2018)
Synthesis and breakdown of universal metabolic precursors promoted by iron
Kamila M B, et al.
Nature, 569, 104-107 (2019)

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