631175

Methyl 6-chloropyridine-3-carboxylate

98%

• Synonym(s): Methyl 6-chloronicotinate, Methyl 6-chloro-3-picolinate
• Empirical Formula (Hill Notation): C₇H₆ClNO₂
• CAS Number: 73781-91-6
• Molecular Weight: 171.58
• MDL number: MFCD00023420
• UNSPSC Code: 12352100
• PubChem Substance ID: 24882393
• NACRES: NA.22

Properties

• Quality Level: 100
• Assay: 98%
• mp: 86-90 °C (lit.)
• functional group: chloro; ester
• SMILES string: COC(=O)c1ccc(Cl)nc1
• InChI: 1S/C7H6ClNO2/c1-11-7(10)5-2-3-6(8)9-4-5/h2-4H,1H3
• InChI key: RMEDXVIWDFLGES-UHFFFAOYSA-N

Description

Application

Methyl 6-chloropyridine-3-carboxylate can be used to synthesize fluoro substituted 6-phenylnicotinamide, which shows TRPV1 antagonist potency. It can also be used in the synthesis of retinoid x receptor (RXR) ligands, which have many clinical applications.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H317,H319
• Precautionary Statements: P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Sens. 1
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves