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Assay
97%
mp
202-205 °C (lit.)
SMILES string
OC(=O)C1=COc2ccccc2C1=O
InChI
1S/C10H6O4/c11-9-6-3-1-2-4-8(6)14-5-7(9)10(12)13/h1-5H,(H,12,13)
InChI key
PCIITXGDSHXTSN-UHFFFAOYSA-N
Gene Information
human ... PTPN1(5770)
General description
Chromone-3-carboxylic acid is a chromone derivative. Its potential as an antioxidant in charge transfer (CT) processes has been assessed by surface-enhanced Raman scattering (SERS) analysis of chromone 3-carboxylic acid adsorbed on silver colloids.
Application
Chromone-3-carboxylic acid may be used in the preparation of:
- chromane-2,4-diones
- chromone-3-carboxamides
- 5-(2-hydroxyphenyl)isoxazole
- chromone-2-carboxamides
- chromone-2-carboxamido-3-esters
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Conjugate addition of isocyanides to chromone 3-carboxylic acid: an efficient one-pot synthesis of chroman-4-one 2-carboxamides.
Organic & Biomolecular Chemistry, 10(17), 3406-3416 (2012)
Chromone-3-carboxylic acid as a potential electron scavenger: a surface-enhanced Raman scattering study.
Physical Chemistry Chemical Physics, 13(3), 1012-1018 (2011)
Synthesis of [1] benzopyrano [3,4-d] isoxazol-4-ones from 2-substituted chromone-3-carboxylic esters. A reinvestigation of the reaction of 3-acyl-4-hydroxycoumarins with hydroxylamine. Synthesis of 4-(2-hydroxybenzoyl) isoxazol-5-ones.
The Journal of Organic Chemistry, 49(23), 4419-4424 (1984)
Chemical communications (Cambridge, England), 51(14), 2832-2835 (2015-01-13)
The discovery of potent and selective monoamine oxidase-B inhibitors for the management of neurodegenerative diseases such as Alzheimer's and Parkinson's diseases is still a challenging endeavor. Herein, we report the discovery of two new classes of potent and selective MAO-B
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