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217808

Sigma-Aldrich

cis-Aconitic anhydride

95%

Synonym(s):

cis-Propene-1,2,3-tricarboxylic anhydride

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About This Item

Empirical Formula (Hill Notation):
C6H4O5
CAS Number:
6318-55-4
Molecular Weight:
156.09
Beilstein:
127575
EC Number:
228-663-3
MDL number:
MFCD00005524
UNSPSC Code:
12162002
PubChem Substance ID:
24853034
NACRES:
NA.23

Assay

95%

mp

75-78 °C (lit.)

SMILES string

OC(=O)CC1=CC(=O)OC1=O

InChI

1S/C6H4O5/c7-4(8)1-3-2-5(9)11-6(3)10/h2H,1H2,(H,7,8)

InChI key

GVJRTUUUJYMTNQ-UHFFFAOYSA-N

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Pictograms

Corrosion
GHS05

Signal Word

Danger

Hazard Statements

H314

Hazard Classifications

Skin Corr. 1B

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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M Wirth et al.
Pharmaceutical research, 15(7), 1031-1037 (1998-08-04)
To investigate the usefulness of wheat germ agglutinin as a targeting carrier protein for an acid-labile chemotherapeutic prodrug directed against colon carcinoma cells in vitro. Cis-aconityl-linked doxorubicin-wheat germ agglutinin was prepared by a two step procedure and the conjugate-binding capacity
Ming Zhao et al.
Natural product communications, 7(6), 785-787 (2012-07-24)
From the seeds of Alisma orientale, cis-aconitic anhydride ethyl ester and cis-2,4,5-trihydroxycinnamic acid were isolated, together with nine known phenolic compounds and a megastigmane sesquiterpene. All compounds are reported for the first time from Alisma species.
A V Martynov et al.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, 25(7), 414-417 (2005-07-19)
The antiproliferative activity of aconitylated (AIFN) and succinylated (SIFN) derivatives of recombinant interferon- alpha2b (IFN-alpha2b) was examined. Acylation of IFN-alpha2b was performed by succinic and cis-aconitic anhydrides. Antiproliferative properties of AIFN and SIFN were studied in vitro on the CaOv
Abhijeet Pandey et al.
Materials science & engineering. C, Materials for biological applications, 98, 419-436 (2019-03-01)
In the present investigation, FePt alloy nanoparticles were synthesized with controlled size and elemental composition followed by surface modification using (3-Aminopropyl) triethoxysilane (APTES). Lenalidomide was covalently bound to FePt-NH2 by pH sensitive hydrazone bonding. Hyaluronic acid was conjugated to amino
J A Kamps et al.
Biochimica et biophysica acta, 1278(2), 183-190 (1996-01-31)
Human serum albumin (HSA) derivatized with cis-aconitic anhydride (Aco-HSA) that was earlier shown to inhibit replication of human immunodeficiency virus type 1 (HIV-1), was covalently coupled to conventional liposomes, consisting of phosphatidylcholine, cholesterol and maleimido-4-(p-phenylbutyryl)phosphatidylethanolamine, using the heterobifunctional reagent N-succinimidyl-S-acetylthioacetate
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