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199257

Sigma-Aldrich

L-(+)-Lactic acid solution

in H2O, ≥85%

Synonym(s):

(S)-(+)-Lactic acid, (S)-2-Hydroxypropionic acid

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About This Item

Linear Formula:
CH3CH(OH)CO2H
CAS Number:
Molecular Weight:
90.08
Beilstein:
1720251
MDL number:
UNSPSC Code:
12161700
PubChem Substance ID:
NACRES:
NA.25

Quality Level

Assay

≥85%

optical activity

[α]20/D −13.5°, c = 2.5 in 1.5 M NaOH

concentration

in H2O

refractive index

n20/D 1.427

density

1.206 g/mL at 25 °C

SMILES string

C[C@H](O)C(O)=O

InChI

1S/C3H6O3/c1-2(4)3(5)6/h2,4H,1H3,(H,5,6)/t2-/m0/s1

InChI key

JVTAAEKCZFNVCJ-REOHCLBHSA-N

Other Notes

Contains varying amounts of intermolecular esterification products
Most salts of L-(+)-lactic acid are levorotatory, hence the negative rotation in NaOH solution.

Pictograms

Corrosion

Signal Word

Danger

Hazard Statements

Hazard Classifications

Eye Dam. 1 - Skin Corr. 1C

Supplementary Hazards

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 1

Flash Point(F)

235.4 °F - closed cup

Flash Point(C)

113 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Franco Valenza et al.
Critical care (London, England), 9(6), 588-593 (2005-12-17)
Lactate measurement in the critically ill has been traditionally used to stratify patients with poor outcome. However, plasma lactate levels are the result of a finely tuned interplay of factors that affect the balance between its production and its clearance.
Melanie C McKell et al.
Frontiers in immunology, 12, 653571-653571 (2021-06-01)
Macrophages are indispensable immune cells tasked at eliminating intracellular pathogens. Mycobacterium tuberculosis (Mtb), one of the most virulent intracellular bacterial pathogens known to man, infects and resides within macrophages. While macrophages can be provoked by extracellular stimuli to inhibit and
T Isotalo et al.
BJU international, 88(1), 30-34 (2001-07-12)
To assess whether patients in acute urinary retention from benign prostatic enlargement can be treated with a combined therapy comprising finasteride and a bioabsorbable self-reinforced poly L-lactic acid (SR-PLLA) urethral stent. Fifty-five patients in acute urinary retention were treated as
Ariadna Montero-Blay et al.
Cell reports, 31(9), 107722-107722 (2020-06-04)
Here, we propose an approach to identify active metabolic pathways by integrating gene essentiality analysis and protein abundance. We use two bacterial species (Mycoplasma pneumoniae and Mycoplasma agalactiae) that share a high gene content similarity yet show significant metabolic differences.
S Walenta et al.
Current medicinal chemistry, 11(16), 2195-2204 (2004-07-29)
A number of studies have demonstrated that malignant transformation is associated with an increase in glycolytic flux and in anaerobic and aerobic cellular lactate excretion. Using quantitative bioluminescence imaging in various primary carcinomas in patients (uterine cervix, head and neck

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