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69311

Supelco

Quinine

certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

Synonym(s):

6′-Methoxycinchonidine

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About This Item

Empirical Formula (Hill Notation):
C20H24N2O2
CAS Number:
130-95-0
Molecular Weight:
324.42
Beilstein:
91867
EC Number:
205-003-2
MDL number:
MFCD00198096
UNSPSC Code:
41116107
PubChem Substance ID:
329761562
NACRES:
NA.24

grade

certified reference material
TraceCERT®

Quality Level

300

product line

TraceCERT®

shelf life

limited shelf life, expiry date on the label

manufacturer/tradename

Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

storage condition

under inert gas

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

173-175 °C (lit.)

application(s)

food and beverages

format

neat

SMILES string

COc1ccc2nccc([C@@H](O)[C@@H]3C[C@@H]4CCN3C[C@@H]4C=C)c2c1

InChI

1S/C20H24N2O2/c1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18/h3-6,8,11,13-14,19-20,23H,1,7,9-10,12H2,2H3/t13-,14-,19-,20+/m0/s1

InChI key

LOUPRKONTZGTKE-WZBLMQSHSA-N

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General description

This certified reference material (CRM) is produced and certified in accordance with ISO/IEC 17025 and ISO 17034. This CRM is traceable to primary material from an NMI, e.g. NIST or NMIJ.
Certified content by quantitative NMR incl. uncertainty and expiry date are given on the certificate.
Download your certificate at: http://www.sigma-aldrich.com.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

Potassium channel blocker

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Caution

Store under argon.

Legal Information

TraceCERT is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302,H317

Hazard Classifications

Acute Tox. 4 Oral - Skin Sens. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

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Certificates of Analysis (COA)

Lot/Batch Number
BCCF7920
BCBV4559
BCBM5794V
BCBG6955V
BCBG6955

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Annemarie R Kreeftmeijer-Vegter et al.
Malaria journal, 12, 115-115 (2013-03-30)
Exchange transfusion (ET) has remained a controversial adjunct therapy for the treatment of severe malaria. In order to assess the relative contribution of ET to parasite clearance in severe malaria, all patients receiving ET as an adjunct treatment to parenteral
Joop E Arends et al.
The American journal of tropical medicine and hygiene, 89(3), 527-530 (2013-07-17)
Recently, two patients of African origin were given a diagnosis of Plasmodium falciparum malaria without recent travel to a malaria-endemic country. This observation highlights the importance for clinicians to consider tropical malaria in patients with fever. Possible transmission routes of
Hmwe Hmwe Kyu et al.
Bulletin of the World Health Organization, 87(12), 896-904 (2010-05-11)
To summarize the existing evidence on the efficacy of artemether and arteether, two artemisinin derivatives, versus quinine for treating cerebral malaria in children. We searched the Cochrane Central Register of Controlled Trials, MEDLINE, EMBASE and the http://clinicaltrials.gov web site. We
Xiong-Li Liu et al.
Organic letters, 15(6), 1246-1249 (2013-03-05)
A wide range of structurally diverse 3,3'-thiopyrrolidonyl spirooxindoles bearing three contiguous stereogenic centers can be smoothly obtained via a domino Michael/cyclization reaction between 3-isothiocyanato oxindoles and 3-methyl-4-nitro-5-alkenyl-isoxazoles with commercially available quinine as the catalyst under mild conditions. The protocol is
Inge Sutanto et al.
Antimicrobial agents and chemotherapy, 57(3), 1128-1135 (2012-12-21)
Radical cure of Plasmodium vivax infection applies blood schizontocidal therapy against the acute attack and hypnozoitocidal therapy against later relapse. Chloroquine and primaquine have been used for 60 years in this manner. Resistance to chloroquine by the parasite now requires
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