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13180

Supelco

Benzylamine

for GC derivatization, LiChropur, ≥99.0%

Synonym(s):

α-Aminotoluene

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About This Item

Linear Formula:
C6H5CH2NH2
CAS Number:
Molecular Weight:
107.15
Beilstein:
741984
EC Number:
MDL number:
UNSPSC Code:
12000000
eCl@ss:
39030404
PubChem Substance ID:
NACRES:
NA.22

grade

for GC derivatization

Quality Level

Assay

≥99.0% (GC)
≥99.0%

form

liquid

quality

LiChropur

technique(s)

gas chromatography (GC): suitable

refractive index

n20/D 1.543 (lit.)
n20/D 1.543

bp

184-185 °C (lit.)

mp

10 °C (lit.)

solubility

H2O: soluble

density

0.981 g/mL at 25 °C (lit.)

SMILES string

NCc1ccccc1

InChI

1S/C7H9N/c8-6-7-4-2-1-3-5-7/h1-5H,6,8H2

InChI key

WGQKYBSKWIADBV-UHFFFAOYSA-N

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General description

Benzylamine, a primary amine, can be used as a fluorescence derivatization agent for the sensitive and selective determination of analytes by chromatography techniques coupled with fluorescence detection.

Application

Benzylamine may be used as a derivatization agent to increase the sensitivity of 5-hydroxyindoles, catecholamines and catechols in biological samples prior to their determination using high performance liquid chromatography (HPLC) coupled with fluorescence detection.

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Legal Information

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

Pictograms

CorrosionExclamation mark

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 1

Flash Point(F)

149.0 °F - closed cup

Flash Point(C)

65 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Simultaneous determination of norepinephrine, serotonin, and 5-hydroxyindole-3-acetic acid in microdialysis samples from rat brain by microbore column liquid chromatography with fluorescence detection following derivatization with benzylamine
Yoshitake T, et al.
Analytical Biochemistry, 312(2), 125-133 (2003)
The Derivatization of Proquinoidal Analytes with 1, 2-Diphenylethane-1, 2-Diamine (DPE) and Benzylamine (BA): An Investigation of Products, Yields, Kinetics and Reagent Selectivity
Woods JM, et al.
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Kaoru Fujino et al.
Journal of chromatography. A, 1012(2), 169-177 (2003-10-03)
A highly selective and sensitive method for the simultaneous determination of 5-hydroxyindoles and catechols (serotonin, norepinephrine, dopamine and related compounds) by high-performance liquid chromatography with fluorescence detection is described. The method is based on the two-step precolumn derivatization of 5-hydroxyindoles
Farid Oukacine et al.
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In an effort to identify novel multifunctional drug candidates for the treatment of Alzheimer's disease (AD), a series of hybrid molecules were synthesised by reacting N-(aminoalkyl)tacrine with salicylic aldehyde or derivatives of 2-aminobenzaldehyde. These compounds were then evaluated as multifunctional

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