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AB4336

Sigma-Aldrich

Anti-SCA-1 Antibody

from rabbit, purified by affinity chromatography

Synonym(s):

Lymphocyte antigen 6A-2/6E-1, Ly-6A.2/Ly-6E.1, T-cell-activating protein, Stem cell antigen 1

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

rat, mouse

technique(s)

immunocytochemistry: suitable
western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

mouse ... Ly6A(110454)

General description

Stem cell antigen 1 (SCA-1) is a membrane protein belonging to the Ly-6 family of proteins and contains a single UPAR/Ly6 domain. SCA-1 is involved in the activation of T-cells and is thought to have a critical role in the differentiation, proliferation, and survival of a variety of stem cells. Recent studies have indicated SCA-1 to be an ideal marker for the isolation and purification of stem cells for research and further characterization. It is expressed by both progenitor and stem cells from several tissue types including; cardiac, hematopoietic, mammary, muscle, skin and testis.

Specificity

No Homology to human was found.
This antibody recognizes SCA-1 at the UPAR/Ly6 domain.

Immunogen

Epitope: UPAR/Ly6 domain
KLH-conjugated linear peptide corresponding to mouse SCA-1 at the UPAR/Ly6 domain.

Application

Anti-SCA-1 Antibody is an antibody against SCA-1 for use in WB & IC.
Immunocytochemistry Analysis: A 1:500 dilution from a previous lot detected SCA-1 in rat mesenchymal stem cells.
Research Category
Stem Cell Research
Research Sub Category
Hematopoietic Stem Cells

Quality

Evaluated by Western Blot in mouse lung tissue lysate.

Western Blot Analysis: 0.1 µg/mL of this antibody detected SCA-1 in 10 µg of mouse lung tissue lysate.

Target description

~14 kDa observed

Physical form

Affinity purified
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.05% sodium azide.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Analysis Note

Control
Mouse lung tissue lysate

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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