845875C

18:1 Lyso PC

1-oleoyl-2-hydroxy-sn-glycero-3-phosphocholine, chloroform

• Synonym(s): 1--(9Z-octadecenoyl)-sn-glycero-3-phosphocholine; PC(18:1(9Z)/0:0); 110688
• Empirical Formula (Hill Notation): C₂₆H₅₂NO₇P
• CAS Number: 19420-56-5
• Molecular Weight: 521.67
• UNSPSC Code: 51191904
• NACRES: NA.25

Properties

• Assay: >99% (LPC; may contain up to 10% of the 2-LPC isomer, TLC)
• form: liquid
• packaging: pkg of 1 × 2.5 mL (845875C-25mg); pkg of 2 × 4 mL (845875C-200mg); pkg of 5 × 4 mL (845875C-500mg)
• manufacturer/tradename: Avanti Research^™ - A Croda Brand 845875C
• concentration: 10 mg/mL (845875C-25mg); 25 mg/mL (845875C-200mg); 25 mg/mL (845875C-500mg)
• shipped in: dry ice
• storage temp.: −20°C
• InChI: 1S/C26H52NO7P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-26(29)32-23-25(28)24-34-35(30,31)33-22-21-27(2,3)4/h12-13,25,28H,5-11,14-24H2,1-4H3/b13-12-/t25-/m1/s1
• InChI key: YAMUFBLWGFFICM-PTGWMXDISA-N

Description

General description

18:1 Lyso PC (1-oleoyl-2-hydroxy-sn-glycero-3-phosphocholine) is an endogenous lipid. It has one hydrocarbon tail.

Application

18:1 Lyso PC (1-oleoyl-2-hydroxy-sn-glycero-3-phosphocholine) has been used to study its effects on eosinophils isolated from healthy human donors/to test its effects on the degranulation-associated processes in eosinophils. It may be used as a lysophospholipid mediator in binding assays and in equilibrium fluorescence peptide-binding assays of the calmodulin (CaM)-target complex.

Biochem/physiol Actions

Lysophosphatidylcholine (LPC) participates as a key factor in the atherogenic activity of oxidized low-density lipoprotein (Ox-LDL). It is a well-known cluster of differentiation 1(CD1) ligand.

Packaging

5 mL Clear Glass Sealed Ampule (845875C-200mg)

5 mL Clear Glass Sealed Ampule (845875C-25mg)

5 mL Clear Glass Sealed Ampule (845875C-500mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Safety Information

• Pictograms: GHS06,GHS08
• Signal Word: Danger
• Hazard Statements: H302,H315,H319,H331,H336,H351,H361d,H372,H412
• Precautionary Statements: P201 - P273 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P308 + P313
• Hazard Classifications: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
• Target Organs: Central nervous system, Liver,Kidney
• WGK: WGK 3