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391220

Sigma-Aldrich

2-Chloro-1,3,2-dioxaphospholane

97%

Synonym(s):

Cyclic ethylene chlorophosphite, Cyclic ethylene phosphorochloridite, Ethylene chlorophosphite, Ethylene glycol chlorophosphite

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About This Item

Empirical Formula (Hill Notation):
C2H4ClO2P
CAS Number:
822-39-9
Molecular Weight:
126.48
Beilstein:
506179
EC Number:
212-499-4
MDL number:
MFCD00014511
UNSPSC Code:
12352005
PubChem Substance ID:
24864368
NACRES:
NA.22

Assay

97%

form

liquid

reaction suitability

reaction type: Buchwald-Hartwig Cross Coupling Reaction
reaction type: Heck Reaction
reaction type: Hiyama Coupling
reaction type: Negishi Coupling
reaction type: Sonogashira Coupling
reaction type: Stille Coupling
reaction type: Suzuki-Miyaura Coupling
reagent type: ligand

refractive index

n20/D 1.489 (lit.)

bp

62 °C/20 mmHg (lit.)

density

1.422 g/mL at 25 °C (lit.)

storage temp.

2-8°C

SMILES string

ClP1OCCO1

InChI

1S/C2H4ClO2P/c3-6-4-1-2-5-6/h1-2H2

InChI key

OLSFRDLMFAOSIA-UHFFFAOYSA-N

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Application

Phosphitylating agent used in the synthesis of phosphocholines and spirophosphoranes.

Pictograms

CorrosionExclamation mark
GHS05,GHS07

Signal Word

Danger

Hazard Statements

H314,H335

Hazard Classifications

Skin Corr. 1B - STOT SE 3

Target Organs

Respiratory system

Supplementary Hazards

EUH014

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 3

Flash Point(F)

186.8 °F - closed cup

Flash Point(C)

86 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Rec. Trav. Chim., 113, 293-293 (1994)
Tetrahedron Letters, 35, 5783-5783 (1994)
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