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O3129

Sigma-Aldrich

N-Octanoyl-N-methylglucamine

≥97% (GC)

Synonym(s):

N-(D-Glucityl)-N-methyloctanamide, N-Methyl-N-octanoyl-D-glucamine, MEGA-8, OMEGA

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About This Item

Empirical Formula (Hill Notation):
C15H31NO6
CAS Number:
Molecular Weight:
321.41
Beilstein:
5816747
MDL number:
UNSPSC Code:
12352201
PubChem Substance ID:
NACRES:
NA.25

description

non-ionic

Assay

≥97% (GC)

form

powder

mol wt

321.41 g/mol

color

white

CMC

58 mM (20-25°C)

solubility

water: 50 mg/mL, clear, colorless

SMILES string

CCCCCCCC(=O)N(C)C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO

InChI

1S/C15H31NO6/c1-3-4-5-6-7-8-13(20)16(2)9-11(18)14(21)15(22)12(19)10-17/h11-12,14-15,17-19,21-22H,3-10H2,1-2H3/t11-,12+,14+,15+/m0/s1

InChI key

SBWGZAXBCCNRTM-CTHBEMJXSA-N

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Application

N-Octanoyl-N-methylglucamine has been used in a study to assess disordered the N-terminus of PKA. It has also been used in a study to investigate the usefulness of sugar surfactants as solubilizing agents in parenteral formulations.
Non-ionic detergent used for the solubilization of proteins

Biochem/physiol Actions

Water soluble detergent with high solubilising power and non-denaturating properties. Readily removed by dialysis.; Does not interfere with the monitoring of proteins at 280 nm.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Christine Breitenlechner et al.
Biochemistry, 43(24), 7743-7749 (2004-06-16)
Protein kinases comprise the major enzyme family critically involved in signal transduction pathways; posttranslational modifications affect their regulation and determine signaling states. The prototype protein kinase A (PKA) possesses an N-terminal alpha-helix (Helix A) that is atypical for kinases and
Assessment of the Diversity of
Jun Chen et al.
Frontiers in microbiology, 8, 1748-1748 (2017-10-03)
Daniel J White et al.
Journal of computational biology : a journal of computational molecular cell biology, 24(9), 874-881 (2017-04-18)
Applying high-throughput sequencing to pathogen discovery is a relatively new field, the objective of which is to find disease-causing agents when little or no background information on disease is available. Key steps in the process are the generation of millions
Maria José de la Cruz Peña et al.
Viruses, 10(3) (2018-03-07)
Single-cell genomics has unveiled the metabolic potential of dominant microbes inhabiting different environments, including the human body. The lack of genomic information for predominant microbes of the human body, such as bacteriophages, hinders our ability to answer fundamental questions about
Meng-Hsien Chuang et al.
Integrative cancer therapies, 16(4), 516-525 (2016-10-05)
JC-001 is a Chinese medicine that has been used to treat liver disease; however, its significance in cancer treatment has not been characterized. In this study, we used an immunocompetent tumor model to characterize the antitumor activity of JC-001. A

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