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M3885

Sigma-Aldrich

MES sodium salt

≥99% (titration)

Synonym(s):

2-(N-Morpholino)ethanesulfonic acid sodium salt, 4-Morpholineethanesulfonic acid sodium salt

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About This Item

Empirical Formula (Hill Notation):
C6H12NNaO4S
CAS Number:
71119-23-8
Molecular Weight:
217.22
Beilstein:
3765682
EC Number:
275-203-2
MDL number:
MFCD00065473
UNSPSC Code:
12161700
eCl@ss:
32129211
PubChem Substance ID:
24896883
NACRES:
NA.25
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Quality Level

400

Assay

≥99% (titration)

form

crystalline powder

impurities

≤8% water content (Karl Fischer)

useful pH range

5.5-6.7

pKa 

6.1

solubility

water: 0.5 g/mL, clear, colorless

application(s)

diagnostic assay manufacturing

SMILES string

[Na+].[O-]S(=O)(=O)CCN1CCOCC1

InChI

1S/C6H13NO4S.Na/c8-12(9,10)6-3-7-1-4-11-5-2-7;/h1-6H2,(H,8,9,10);/q;+1/p-1

InChI key

IRHWMYKYLWNHTL-UHFFFAOYSA-M

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General description

MES sodium salt is commonly employed as buffer. Useful pH range for MES sodium salt is 5.5 to 6.7.

Application

MES sodium salt is suitable for cell culture and diagnostic assay manufacturing. It was used to prepare buffer to study the expression profiling by microarrays. It may be used as buffer to investigate the enzymatic degradation of DNA to nucleosides by P1 nuclease.[1]

Other Notes

Easily compare specifications for MES sodium salt products with the MES sodium salt specification table.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
0000372344
0000422035
0000422035
0000372344
0000405176

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Precise measurement of the G+ C content of deoxyribonucleic acid by high-performance liquid chromatography.
Mesbah M, et al.
International J. Systemic Bact., 39(2), 159-167 (1989)
Bianca Santos Henriques et al.
Frontiers in physiology, 11, 509310-509310 (2021-02-02)
Rhodnius prolixus is one important vector for the parasite Trypanosoma cruzi in Latin America, where Chagas disease is a significant health issue. Although R. prolixus is a model for investigations of vector-parasite interaction and transmission, not much has been done
Christian Engelbrekt et al.
Chemphyschem : a European journal of chemical physics and physical chemistry, 11(13), 2844-2853 (2010-08-18)
Monodisperse platinum nanoparticles (PtNPs) were synthesized by a green recipe. Glucose serves as a reducing agent and starch as a stabilization agent to protect the freshly formed PtNP cores in buffered aqueous solutions. Among the ten buffers studied, 2-(N-morpholino)ethanesulfonic acid
Elisabet Fuguet et al.
Electrophoresis, 29(13), 2841-2851 (2008-06-12)
The performance of the most common and also some other less common CE buffers has been tested for the pKa determination of several types of compounds (pyridine, amines, and phenols). The selected buffers cover a pH ranging from 3.7 to
Pasi S Vuorinen et al.
Journal of chromatography. A, 990(1-2), 45-52 (2003-04-11)
A contactless conductivity detector integrated into the capillary cassette of Agilent (3D)CE equipment is described. The detector is user-friendly, compact and easily modified. The UV detector of the (3D)CE equipment is available parallel with the contactless conductivity detector increasing the
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Questions

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  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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