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Supelco

Decoquinate

VETRANAL®, analytical standard

Synonym(s):

Ethyl 6-decyloxy-7-ethoxy-4-hydroxy-3-quinolinecarboxylate

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About This Item

Empirical Formula (Hill Notation):
C24H35NO5
CAS Number:
Molecular Weight:
417.54
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

SMILES string

CCCCCCCCCCOc1cc2c(O)c(cnc2cc1OCC)C(=O)OCC

InChI

1S/C24H35NO5/c1-4-7-8-9-10-11-12-13-14-30-21-15-18-20(16-22(21)28-5-2)25-17-19(23(18)26)24(27)29-6-3/h15-17H,4-14H2,1-3H3,(H,25,26)

InChI key

JHAYEQICABJSTP-UHFFFAOYSA-N

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General description

Decoquinate is a quinolone coccidiostat used in poultry, to retard the growth of coccidian parasites and can also show activity against Plasmodium falciparum parasite, which causes malaria in humans.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

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Hazard Statements

Precautionary Statements

Hazard Classifications

Aquatic Chronic 4

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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R B Williams
International journal for parasitology, 27(1), 101-111 (1997-01-01)
The anticoccidial mode of action of quinolones (6-decyloxy-4-hydroxyquinoline-3-carboxylates) against Eimeria tenella and E. acervulina in chickens has been investigated, using decoquinate and M&B 15,584 as examples. The well known static effect on sporozoites of relatively high continuous drug concentrations in
R B Williams
Veterinary parasitology, 135(1), 1-14 (2005-11-18)
Decoquinate is a quinolone coccidiostat introduced during 1967 as an in-feed prophylactic for broiler chickens. Despite early drug-resistance problems and its age, the drug is still used commercially worldwide. Decoquinate here serves as a valuable model in a field study
Questions limitation in treatment of hepatozoonosis.
Nancy Vincent-Johnson
Journal of the American Veterinary Medical Association, 226(12), 1979-1979 (2005-07-02)
Tracing the emergence of drug-resistance in coccidia (Eimeria spp.) of commercial broiler flocks medicated with decoquinate for the first time in the United Kingdom
Williams.B.R
Veterinary Parasitology, 135, 1-14 (2006)
A chemical genomic analysis of decoquinate, a Plasmodium falciparum cytochrome b inhibitor
Nam T-G, et al.
ACS Chemical Biology, 6, 1214-1222 (2011)

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