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Key Documents

8.22325

Sigma-Aldrich

4′-Hydroxyacetanilide

for synthesis

Synonym(s):

4′-Hydroxyacetanilide

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About This Item

Linear Formula:
CH3CONHC6H4(OH)
CAS Number:
Molecular Weight:
151.16
MDL number:
UNSPSC Code:
12352111
EC Index Number:
203-157-5
NACRES:
NA.22

Quality Level

Assay

≥99.0% (HPLC)

form

powder

autoignition temp.

540 °C

potency

1944 mg/kg LD50, oral (Rat)

expl. lim.

15 % (v/v)

pH

5.5-6.5 (20 °C in H2O, saturated solution)

mp

169-170 °C

solubility

14 g/L

density

1.293 g/cm3 at 21 °C

storage temp.

2-30°C

InChI

1S/C8H9NO2/c1-6(10)9-7-2-4-8(11)5-3-7/h2-5,11H,1H3,(H,9,10)

InChI key

RZVAJINKPMORJF-UHFFFAOYSA-N

Application


  • A Review on the Properties and Uses of Paracetamol: This article provides a comprehensive overview of paracetamol, detailing its critical properties and varied uses in the pharmaceutical industry. (Ogemdi, 2019).

  • Development and Validation of a Chromatographic Method for Estimating Paracetamol: Discusses a method for simultaneous estimation of paracetamol and other compounds, highlighting its pharmacological significance. (Navneet Kumar et al., 2017).

  • Quality Assessment of Paracetamol Tablets: Evaluates the quality of different brands of paracetamol tablets in the Yemeni market, crucial for consumer safety. (Ali Alyahawi et al., 2018).

Analysis Note

Assay (HPLC, area%): ≥ 99.0 % (a/a)
Melting range (lower value): ≥ 168 °C
Melting range (upper value): ≤ 172 °C
Identity (IR): passes test

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

364.3 °F - Pensky-Martens closed cup

Flash Point(C)

184.6 °C - Pensky-Martens closed cup


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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