QBD10243
Fmoc-N-amido-dPEG®2-acid
>95% (HPLC)
Synonym(s):
Fmoc-N-amido-PEG2-COOH, Fmoc-N-amido-PEG2-acid, Fmoc-PEG-acid, Fmoc-PEG2-acid
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About This Item
Empirical Formula (Hill Notation):
C22H25NO6
Molecular Weight:
399.44
MDL number:
UNSPSC Code:
12352106
NACRES:
NA.22
Assay
>95% (HPLC)
form
solid or viscous liquid
reaction suitability
reaction type: Pegylations
polymer architecture
shape: linear
functionality: homobifunctional
shipped in
ambient
storage temp.
−20°C
Features and Benefits
Fmoc-N-amido-dPEG2-acid is a monodisperse PEG product that is useful for peptide synthesis. The ten-atom dPEG spacer allows the introduction of a short, hydrophilic spacer onto either end of a peptide chain or between two peptide chains. The flexible dPEG spacer conjugates to peptides using conventional peptide synthesis chemistry. Peptide PEGylation imparts water solubility to hydrophobic peptide chains. Also, PEGylated peptides have expanded hydrodynamic volumes, which can reduce or eliminate renal clearance, and are protected from proteolysis. The combination of decreased renal clearance and protection from proteolysis contributes to longer in vivo circulation times for PEGylated (as compared to non-PEGylated) peptides. Additionally, PEGylation diminishes a peptide′s antigenicity. This product is part of the Fmoc-N-amido-dPEGn-acid (n=2, 3, 4, 5, 6, 8, 12, 24, 36) product series.
Legal Information
Products Protected under U.S. Patent #s 7,888,536 & 8,637,711 and European Patent #s 1,594,440 & 2,750,681
dPEG is a registered trademark of Quanta BioDesign
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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