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D12805

Sigma-Aldrich

3,5-Diaminobenzoic acid

98%, for peptide synthesis

Synonym(s):

3,5-DABA, 5-Carboxy-1,3-phenylenediamine, DABA

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About This Item

Linear Formula:
(H2N)2C6H3CO2H
CAS Number:
Molecular Weight:
152.15
Beilstein:
2086484
EC Number:
MDL number:
UNSPSC Code:
12352106
PubChem Substance ID:
NACRES:
NA.22

product name

3,5-Diaminobenzoic acid, 98%

Assay

98%

form

powder with small lumps

reaction suitability

reaction type: solution phase peptide synthesis

mp

235-238 °C (dec.) (lit.)

application(s)

peptide synthesis

SMILES string

Nc1cc(N)cc(c1)C(O)=O

InChI

1S/C7H8N2O2/c8-5-1-4(7(10)11)2-6(9)3-5/h1-3H,8-9H2,(H,10,11)

InChI key

UENRXLSRMCSUSN-UHFFFAOYSA-N

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Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Céline Douat-Casassus et al.
Journal of the American Chemical Society, 126(25), 7817-7826 (2004-06-24)
Peptide dendrimers incorporating 3,5-diaminobenzoic acid 1 as a branching unit (B) were prepared by solid-phase synthesis of ((Ac-A(3))(2)B-A(2))(2)B-Cys-A(1)-NH(2) followed by disulfide bridge formation. Twenty-one homo- and heterodimeric dendrimers were obtained by permutations of aspartate, histidine, and serine at positions A(1)
J Beckmann et al.
Acta diabetologica latina, 18(1), 51-57 (1981-01-01)
DNA content seems to be an ideal reference parameter for data on secretory function or metabolism of pancreatic islets. The approved fluorometric DNA assay with diaminobenzoic acid (DABA) of Kissane and Robins comprises repeated ethanol extractions of the tissue for
[Improved fluorometric method for DNA microanalysis].
M M Vilenchik et al.
Izvestiia Akademii nauk SSSR. Seriia biologicheskaia, (2)(2), 217-222 (1984-03-01)
Interference of Bis-Tris buffer with the diaminobenzoic acid fluorescence assay used to quantify DNA.
W E Schy et al.
Mutation research, 226(4), 263-266 (1989-08-01)
Wei-Yu Chen et al.
Analytical chemistry, 75(16), 4223-4228 (2003-11-25)
The alkali cation adductions of oligonucleotides dramatically degrade MALDI mass spectra and even affect the detection limit. Desalting is generally involved in MALDI sample preparation. This work demonstrates the feasibility of using 3,4-diaminobenzoic acid (DABA) and 3,5-DABA as the MALDI

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