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219576

Sigma-Aldrich

(1S)-(+)-10-Camphorsulfonyl chloride

97%

Synonym(s):

(+)-Camphor-10-sulfonyl chloride, (1S)-Camphor-10-sulfonic acid chloride

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About This Item

Empirical Formula (Hill Notation):
C10H15ClO3S
CAS Number:
Molecular Weight:
250.74
Beilstein:
3205974
EC Number:
MDL number:
UNSPSC Code:
12352115
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

97%

form

solid

mp

65-67 °C (lit.)

SMILES string

[H][C@@]12CC[C@@](CS(Cl)(=O)=O)(C(=O)C1)C2(C)C

InChI

1S/C10H15ClO3S/c1-9(2)7-3-4-10(9,8(12)5-7)6-15(11,13)14/h7H,3-6H2,1-2H3/t7-,10-/m1/s1

InChI key

BGABKEVTHIJBIW-GMSGAONNSA-N

Application

Chiral resolving agent. Used in the synthesis of nonpeptide oxytocin antagonists.

Pictograms

Corrosion

Signal Word

Danger

Hazard Statements

Hazard Classifications

Skin Corr. 1B

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Synthesis, 947-947 (1992)
B E Evans et al.
Journal of medicinal chemistry, 35(21), 3919-3927 (1992-10-16)
The first nonpeptide antagonists of the neurohypophyseal hormone, oxytocin (OT) are described. Derivatives of the spiroindenepiperidine ring system, these compounds include L-366,509, an orally bioavailable OT antagonist with good in vivo duration. The potential use of these agents for treatment
T Jira et al.
Die Pharmazie, 48(11), 829-833 (1993-11-01)
Investigations on direct separation by RP-HPLC of selected enantiomeric beta-adrenergic active agents are described. R- and S-1-phenylethylisocyanate (PEIC) as well as (1S)-(+)-campher-10-sulfonylchloride (CSC) are used for the derivatization of the compounds. Correlations between chromatographic data and various influences (pH, temperature

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