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Key Documents

200654

Sigma-Aldrich

Ethyl cellulose

viscosity 300 cP, 5 % in toluene/ethanol 80:20(lit.), extent of labeling: 48% ethoxyl

Synonym(s):

Ethylcellulose

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About This Item

CAS Number:
MDL number:
UNSPSC Code:
12162002
NACRES:
NA.23

form

granular

Quality Level

autoignition temp.

698 °F

concentration

48.0-49.5%

extent of labeling

48% ethoxyl

refractive index

n20/D 1.47 (lit.)

viscosity

300 cP, 5 % in toluene/ethanol 80:20(lit.)

transition temp

softening point 157 °C

density

1.14 g/mL at 25 °C (lit.)

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General description

Ethyl cellulose (EC) is a non-toxic, biocompatible, and hydrophobic polymer used for the sustained release preparation of pharmaceutical products.

Application

Ethyl cellulose can be used to prepare polymer coatings for various applications. For example, it is used to encapsulate salt hydrates for low-temperature heat storage applications.

It can be used as an efficient carrier for multiparticulate sustained drug delivery. For example, it can be used to develop polymeric microspheres for the controlled release of Ivabradine HCL (IBH).

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Dace Gao et al.
Nanoscale horizons, 5(4), 730-738 (2020-02-18)
The design and construction of 3D architectures enabled by stimuli-responsive soft materials can yield novel functionalities for next generation soft-bodied actuating devices. Apart from additive manufacturing processes, origami inspired technology offers an alternative approach to fabricate 3D actuators from planar
Daniela Traini et al.
International journal of pharmaceutics, 438(1-2), 150-159 (2012-09-12)
The potential of excipient coating to enhance aerosol performance of micronized drugs in carrier excipient-drug blends, used in dry powder inhalers, was investigated. Both EC (ethyl cellulose) and PVP (polyvinylpyrrolidone) were used as coating agents. Carriers were prepared via sieve
N Suwannateep et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 82(3), 485-490 (2012-09-08)
The phytochemical curcumin possesses antioxidant activity; however, it becomes unstable after being exposed to light or heat or loses activity during storage. This is especially important when curcumin is applied to the skin within a cosmetic or pharmaceutical formulation, since
Helene Andersson et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 48(1-2), 240-248 (2012-11-20)
Films of ethyl cellulose (EC) and water-soluble hydroxypropyl cellulose (HPC) can be used for extended release coatings in oral formulations. The permeability and microstructure of free EC/HPC films with 30% w/w HPC were studied to investigate effects of EC molecular
Tetsuya Ozeki et al.
Biological & pharmaceutical bulletin, 35(11), 1926-1931 (2012-11-06)
Production of drug nanoparticles is an effective strategy to enhance solubility and oral absorption of water-insoluble drugs. The handling of drug nanoparticles has been an important issue in drug formulation because nanoparticles easily aggregate each other and redispersion of these

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