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94119

Supelco

Glycine

analytical standard, for nitrogen determination according to Kjeldahl method

Synonym(s):

2-Aminoacetic acid, Aminoacetic acid, Aminoethanoic acid, Glycocoll

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About This Item

Linear Formula:
NH2CH2COOH
CAS Number:
56-40-6
Molecular Weight:
75.07
Beilstein:
635782
EC Number:
200-272-2
MDL number:
MFCD00008131
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
329770301
NACRES:
NA.24
Pricing and availability is not currently available.

grade

analytical standard

Quality Level

100

Assay

≥99.0%

analyte chemical class(es)

amino acids, peptides, proteins

technique(s)

HPLC: suitable
gas chromatography (GC): suitable
titration: suitable

impurities

18.6%±0.2% total nitrogen acc. to Kjeldahl

loss

≤0.05% loss on drying

pKa (25 °C)

(1) 2.35, (2) 9.60
2.35

mp

240 °C (dec.) (lit.)

solubility

1 M HCl: 75 mg/L, clear, colorless (2.252g in 30mL)

anion traces

chloride (Cl-): ≤50 mg/kg

cation traces

NH4+: ≤200 mg/kg

application(s)

food and beverages

format

neat

SMILES string

NCC(O)=O

InChI

1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)

InChI key

DHMQDGOQFOQNFH-UHFFFAOYSA-N

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General description

The glycine standard is produced under stringent conditions and measured with the highest possible precision.

Application

It can be used as an analytical standard to:
  • Evaluate Kjeldahl′s procedure to determine total protein content of reference standards used in clinical laboratories.
  • Analyze beer and wine for their protein and total usable nitrogen using a microwell ninhydrin assay.
  • Compare Kjeldahl and Dumas methods for routine analysis of dairy products in an interlaboratory study.
  • Simultaneously determine total phosphorus and total Kjeldahl nitrogen in surface water samples.
  • Quantitatively determine nitrate in surface waters using Valdetrama method.
  • Measure low level Kjeldahl nitrogen using an AutoAnalyzer.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

Inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors.

Features and Benefits

  • Available in a neat format in a secure glass bottle to ensure its stability for the entire shelf life until opened.
  • High-quality offering accurate titer determinations

Recommended products

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 1

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCL3514
BCCL2694
BCCK0166
BCCF5788
BCCC9241

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The Structure of Glycine Dihydrate: Implications for the Crystallization of Glycine from Solution and Its Structure in Outer Space
Xu W, et al.
Angewandte Chemie (Weinheim an der Bergstrasse, Germany), 129, 2062-2066 (2017)
Structure of Glycine Dihyrate: Its Implications to Crystallization of Glycine from Solution and Modification of Glycine in Space
Hu.T.C, et al.
Acta Crystallographica Section A, Foundations of Crystallography, 73 (2017)
Alexander Carvajal-González et al.
Brain : a journal of neurology, 137(Pt 8), 2178-2192 (2014-06-22)
The clinical associations of glycine receptor antibodies have not yet been described fully. We identified prospectively 52 antibody-positive patients and collated their clinical features, investigations and immunotherapy responses. Serum glycine receptor antibody endpoint titres ranged from 1:20 to 1:60 000.
Li-Chun Tu et al.
The EMBO journal, 32(24), 3220-3230 (2013-11-12)
Nuclear pore complexes (NPCs) mediate cargo traffic between the nucleus and the cytoplasm of eukaryotic cells. Nuclear transport receptors (NTRs) carry cargos through NPCs by transiently binding to phenylalanine-glycine (FG) repeats on intrinsically disordered polypeptides decorating the NPCs. Major impediments
Suzanne L Grant et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 844(2), 278-282 (2006-08-08)
A simple and versatile methodology using high-performance liquid chromatography (HPLC) with fluorimetric detection was developed to simultaneously determine d-serine along with other metabolically related neuroactive amino acids in the glutamatergic system: L-serine, L-glutamate, L-glutamine, and glycine. On-column sensitivity was in
View All Related Papers

Questions

1–2 of 2 Questions  

  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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