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Sigma-Aldrich

L-(+)-Lactic acid

80%

Synonym(s):

(S)-2-Hydroxypropionic acid, Sarcolactic acid

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About This Item

Empirical Formula (Hill Notation):
C3H6O3
CAS Number:
Molecular Weight:
90.08
Beilstein:
1720251
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.21

Quality Level

Assay

80%

form

liquid

ign. residue

≤0.1% (as SO4)

solubility

water: soluble(lit.)

anion traces

chloride (Cl-): ≤50 mg/kg
sulfate (SO42-): ≤100 mg/kg

cation traces

Ca: ≤100 mg/kg
Fe: ≤10 mg/kg

antibiotic activity spectrum

Gram-negative bacteria

Mode of action

cell membrane | interferes

SMILES string

C[C@H](O)C(O)=O

InChI

1S/C3H6O3/c1-2(4)3(5)6/h2,4H,1H3,(H,5,6)/t2-/m0/s1

InChI key

JVTAAEKCZFNVCJ-REOHCLBHSA-N

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Application


  • Pharmaceutical and biomaterial applications: L-(+)-Lactic acid enhances M2 macrophage polarization through regulation of the PCK2/AMPK/mTOR signaling pathway in poly-L-lactic acid membranes, indicating its vital role in biomedicine and materials science (Tang et al., 2024).

  • Agricultural biotechnology: The induction of defense responses in tobacco against Phytophthora nicotianae by L-(+)-Lactic acid underscores its potential application in agricultural biotechnology for plant disease management (Yan et al., 2024).



Biochem/physiol Actions

Use as a substrate for the lactic acid dehydrogenase enzymes.

Pictograms

Corrosion

Signal Word

Danger

Hazard Statements

Hazard Classifications

Eye Dam. 1 - Skin Corr. 1

Supplementary Hazards

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 1

Flash Point(F)

230.0 °F

Flash Point(C)

110 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Recovery of L-(+)-lactic acid by anion exchange resin Amberlite IRA-400.
Cao X, et al.
Biochemical Engineering Journal, 11(2), 189-196 (2002)
Synthesis and characterization of pH-sensitive hydrogels based on chitosan and D, L-lactic acid.
Qu X, et al.
Journal of Applied Polymer Science, 74(13), 3193-3202 (1999)
Swelling and hydrolytic degradation of poly (D, L-lactic acid) in aqueous solutions.
Proikakis C S, et al.
Polymer Degradation and Stability, 91(3), 614-619 (2006)
Carlos Carmona-Fontaine et al.
Proceedings of the National Academy of Sciences of the United States of America, 114(11), 2934-2939 (2017-03-02)
The genetic and phenotypic diversity of cells within tumors is a major obstacle for cancer treatment. Because of the stochastic nature of genetic alterations, this intratumoral heterogeneity is often viewed as chaotic. Here we show that the altered metabolism of
T Isotalo et al.
BJU international, 88(1), 30-34 (2001-07-12)
To assess whether patients in acute urinary retention from benign prostatic enlargement can be treated with a combined therapy comprising finasteride and a bioabsorbable self-reinforced poly L-lactic acid (SR-PLLA) urethral stent. Fifty-five patients in acute urinary retention were treated as

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