437018

N-Boc-1,6-hexanediamine hydrochloride

97%

• Synonym(s): N-Boc-1,6-diamino-hexane hydrochloride, tert-Butyl N-(6-aminohexyl)carbamate hydrochloride
• Linear Formula: (CH₃)₃COCONH(CH₂)₆NH₂ · HCl
• CAS Number: 65915-94-8
• Molecular Weight: 252.78
• Beilstein: 3631740
• EC Number: 265-976-4
• MDL number: MFCD00039072
• UNSPSC Code: 12352116
• PubChem Substance ID: 24867340
• NACRES: NA.22

Properties

• Quality Level: 200
• Assay: 97%
• form: solid
• reaction suitability: reagent type: cross-linking reagent
• mp: 162-164 °C (lit.)
• functional group: Boc; amine
• SMILES string: NCCCCCCNC(OC(C)(C)C)=O.[H]Cl
• InChI: 1S/C11H24N2O2.ClH/c1-11(2,3)15-10(14)13-9-7-5-4-6-8-12;/h4-9,12H2,1-3H3,(H,13,14);1H
• InChI key: JSBWQIZQJOQPFN-UHFFFAOYSA-N

Description

Application

N-Boc-1,6-hexanediamine hydrochloride is a general reagent to introduce a C₆-spacer. It can be used in:

• Synthesis of poly(L-glutamic acid) gadolinium chelates as biodegradable MRI contrast agents.
• Synthesis of cholesteryl-functionalized hyaluronic acid-based anionic nanogel for protein delivery.
• Preparation of amphiphilic prodrug, containing anticancer drug chlorambucil, which would self-assemble to form micelles in aqueous solution.

Reagent for the introduction of a C₆-spacer.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves