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228559

Sigma-Aldrich

3-Phosphonopropionic acid

technical grade, 94%

Synonym(s):

2-Carboxyethanephosphonic acid

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About This Item

Linear Formula:
(HO)2P(O)CH2CH2COOH
CAS Number:
5962-42-5
Molecular Weight:
154.06
EC Number:
227-738-8
MDL number:
MFCD00002770
UNSPSC Code:
12352100
PubChem Substance ID:
24853694
NACRES:
NA.22

grade

technical grade

Assay

94%

form

solid

SMILES string

OC(=O)CCP(O)(O)=O

InChI

1S/C3H7O5P/c4-3(5)1-2-9(6,7)8/h1-2H2,(H,4,5)(H2,6,7,8)

InChI key

NLBSQHGCGGFVJW-UHFFFAOYSA-N

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Application

3-Phosphonopropionic acid was used to functionalize the bulk phosphate glass surface.

Pictograms

Corrosion
GHS05

Signal Word

Danger

Hazard Statements

H314

Hazard Classifications

Eye Dam. 1 - Skin Corr. 1B

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 3

Flash Point(F)

302.0 °F - closed cup

Flash Point(C)

150 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Serena Donnini et al.
Proteins, 76(1), 138-150 (2008-12-18)
When estimating binding affinities of a ligand, which can exists in multiple forms, for a target molecule, one must consider all possible competing equilibria. Here, a method is presented that estimates the contribution of the protonation equilibria of a ligand
Magdalena Osial et al.
Nanomaterials (Basel, Switzerland), 8(6) (2018-06-15)
The exceptional magnetic properties of superparamagnetic iron oxide nanoparticles (SPIONs) make them promising materials for biomedical applications like hyperthermia, drug targeting and imaging. Easy preparation of SPIONs with the controllable, well-defined properties is a key factor of their practical application.
H T Schmidt et al.
Journal of microencapsulation, 23(7), 769-781 (2006-11-25)
Hollow calcium phosphate nanoparticles capable of encapsulating poorly water-soluble molecules were produced by self-assembly. Previously reported were solid calcium phosphate nanoparticles and water-filled calcium phosphate nanocapsules suited for encapsulating mostly hydrophilic, but not hydrophobic compounds. Here, calcium phosphate was deposited
Charles E McKenna et al.
Journal of medicinal chemistry, 53(9), 3454-3464 (2010-04-17)
3-(3-Pyridyl)-2-hydroxy-2-phosphonopropanoic acid (3-PEHPC, 1) is a phosphonocarboxylate (PC) analogue of 2-(3-pyridyl)-1-hydroxyethylidenebis(phosphonic acid) (risedronic acid, 2), an osteoporosis drug that decreases bone resorption by inhibiting farnesyl pyrophosphate synthase (FPPS) in osteoclasts, preventing protein prenylation. 1 has lower bone affinity than 2
M S Hasan et al.
Journal of biomedical materials research. Part A, 101(11), 3301-3310 (2013-08-29)
Fully resorbable phosphate glass fiber reinforced polymer composites have shown real potential for replacing some of the existing metallic bone fracture fixation devices. However, some of these composites have not provided suitable mechanical strength profiles over the required healing period
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