RAB0458
Human Thyroglobulin ELISA Kit
for serum, plasma, cell culture supernatants and urine
Synonym(s):
TGF-beta-1, Thyroglobulin
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About This Item
UNSPSC Code:
41116158
NACRES:
NA.77
Recommended Products
species reactivity
human
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable
capture ELISA: suitable
input
sample type urine
sample type plasma
sample type cell culture supernatant(s)
sample type serum
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 220 pg/mL
standard curve range: 0.205-50 ng/mL
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... TG(7038)
General description
The Human Thyroglobulin ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human Thyroglobulin in serum, plasma, cell culture supernatants and urine.
Immunogen
Recombinant Human Thyroglobulin
Application
For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Human Thyroglobulin ELISA Kit has been used to measure the secreted thyroglobulin (TG) level in primary human thyrocytes.
Biochem/physiol Actions
Thyroglobulin (TG) is a prothyroid hormone. It plays a vital role in production of L-thyroxine (tetraiodothyronine, T4) and L-triiodothyronine (T3) hormones in thyroid gland. Tyrosyls of TG acts as substrate for iodination and hormone formation. Serum thyroglobulin level is used as marker of metastases in differentiated thyroid carcinomas. Mutation in the gene is associated with the development of congenital goitrous hypothyroidism and non-endemic simple goitre.
Other Notes
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
Kit Components Also Available Separately
Product No.
Description
SDS
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Met. Corr. 1
Storage Class Code
8A - Combustible corrosive hazardous materials
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Kathleen M Aicher et al.
PloS one, 14(2), e0212638-e0212638 (2019-02-28)
Gallbladder mucocele formation is an emerging disease in dogs characterized by increased secretion of condensed granules of gel-forming mucin by the gallbladder epithelium and formation of an abnormally thick mucus that can culminate in obstruction of the bile duct or
Thyroglobulin gene point mutation associated with non-endemic simple goitre.
Corral J, et al.
Lancet, 341(8843), 462-464 (1993)
Thyrotropin and insulin-like growth factor 1 receptor crosstalk upregulates sodium?iodide symporter expression in primary cultures of human thyrocytes.
Morgan S J, et al.
Thyroid, 26(12), 1794-1803 (2016)
Role of extracellular molecular chaperones in the folding of oxidized proteins refolding of colloidal thyroglobulin by protein disulfide isomerase and immunoglobulin heavy chain-binding protein.
Delom F, et al.
The Journal of Biological Chemistry, 276(24), 21337-21342 (2001)
A nonsense mutation causes human hereditary congenital goiter with preferential production of a 171-nucleotide-deleted thyroglobulin ribonucleic acid messenger.
Targovnik H M, et al.
The Journal of Clinical Endocrinology and Metabolism, 77(1), 210-215 (1993)
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