933090
NanoFabTx™ NanoFlash PEG-PCL drug formulation screening kit
for CIJ synthesis of nanoparticles
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About This Item
UNSPSC Code:
12162002
NACRES:
NA.21
Recommended Products
storage temp.
2-8°C
Application
NanoFabTx™ NanoFlash PEG-PCL drug formulation screening kit is a ready to use nanoformulation kit for flash nanoprecipitation synthesis of PEGylated poly(caprolactone) (PCL) nanoparticles for drug delivery research applications. This kit contains rationally selected PEGylated PCL polymers and stabilizer, enabling users to screen and select nanoformulations without the need for lenghty trial and error optimization. These PEGylated PCL polymers have been widely used in drug delivery systems for controlled drug release of many different types of therapeutic molecules.
This kit has been curated and designed for flash nanoprecipitiaton (FNP) nanoparticle synthesis using a confined impingement jet (CIJ) mixer, such as the NanoFabTx™ NanoFlash CIJ Mixer, and detailed step-by-step instructions are provided.
This kit has been curated and designed for flash nanoprecipitiaton (FNP) nanoparticle synthesis using a confined impingement jet (CIJ) mixer, such as the NanoFabTx™ NanoFlash CIJ Mixer, and detailed step-by-step instructions are provided.
Features and Benefits
- Ready-to-use nanoformulation kit for PEGylated nanoparticles
- Step-by-step flash nanoprecipitation protocol
- Create specifically sized, biodegradable, PEGylated PCL nanoparticles
- Maximize the encapsulation of hydrophobic drugs
- Three different PEGylated PCL polymers are included
- Optimized for 60 nm-150 nm nanoparticles
Legal Information
NANOFABTX is a trademark of Sigma-Aldrich Co. LLC
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Jing Han et al.
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Johnson and Prud'homme (2003. AICHE J 49:2264-2282) introduced the confined impingement jets (CIJ) mixer to prepare nanoparticles loaded with hydrophobic compounds (e.g., drugs, inks, fragrances, or pheromones) via flash nanoprecipitation (FNP). We have modified the original CIJ design to allow
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