158186
Ethylenediamine-N,N′-diacetic acid
≥98%
Synonym(s):
EDDA, N,N′-Ethylenediglycine
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About This Item
Linear Formula:
HOOCCH2NHCH2CH2NHCH2COOH
CAS Number:
Molecular Weight:
176.17
Beilstein:
1778355
EC Number:
MDL number:
UNSPSC Code:
12352116
PubChem Substance ID:
NACRES:
NA.22
Recommended Products
Quality Level
Assay
≥98%
mp
224 °C (dec.) (lit.)
functional group
amine
carboxylic acid
SMILES string
OC(=O)CNCCNCC(O)=O
InChI
1S/C6H12N2O4/c9-5(10)3-7-1-2-8-4-6(11)12/h7-8H,1-4H2,(H,9,10)(H,11,12)
InChI key
IFQUWYZCAGRUJN-UHFFFAOYSA-N
Application
Ethylenediamine-N,N′-diacetic acid (EDDA) is a chelating agent that can be used to synthesize:
- Binary and ternary copper(II) complexes with potent proteasome inhibitory properties.
- Pd(EDDA) complexes which can coordinate with amino acids, peptides, or DNA units.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Hoi-Ling Seng et al.
Journal of inorganic biochemistry, 102(11), 1997-2011 (2008-09-10)
The binding selectivity of the M(phen)(edda) (M=Cu, Co, Ni, Zn; phen=1,10-phenanthroline, edda=ethylenediaminediacetic acid) complexes towards ds(CG)(6), ds(AT)(6) and ds(CGCGAATTCGCG) B-form oligonucleotide duplexes were studied by CD spectroscopy and molecular modeling. The binding mode is intercalation and there is selectivity towards
Karla Mettrick et al.
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Targeting the iron requirement of Pseudomonas aeruginosa may be an effective adjunctive for conventional antibiotic treatment against biofilm-dwelling P. aeruginosa. We, therefore, assessed the anti-biofilm activity of N,N'-bis (2-hydroxybenzyl) ethylenediamine-N,N'-diacetic acid (HBED), which is a synthetic hexadentate iron chelator. The
Giuseppe Palladino et al.
Dalton transactions (Cambridge, England : 2003), (43)(43), 5176-5183 (2006-11-02)
The structure, thermodynamics and kinetics of the binary and ternary uranium(VI)-ethylenediamine-N,N'-diacetate (in the following denoted EDDA) fluoride systems have been studied using potentiometry, 1H, 19F NMR spectroscopy and X-ray diffraction. The UO2(2+)-EDDA system could be studied up to -log[H3O+] =
Alma D Miranda-Olvera et al.
Bioconjugate chemistry, 18(5), 1560-1567 (2007-08-02)
Two synthetic procedures for HYNIC oxytocin labeling were developed: one based on an orthogonal protection approach and the other with prelabeled (Boc)HYNIC-(Fmoc) amino acids. Both procedures were compared and applied to the preparation of several HYNIC-oxytocin derivatives where ligand position
Jelena M Vujić et al.
European journal of medicinal chemistry, 45(9), 3601-3606 (2010-06-24)
Four novel bidentate N,N'-ligand precursors, including O,O'-dialkyl esters (alkyl = ethyl, n-propyl, n-butyl and n-pentyl), L1 x 2 HCl-L4 x 2 HCl, of (S,S)-ethylenediamine-N,N'-di-2-(4-methyl)-pentanoic acid dihydrochloride [(S,S)-H(4)eddl]Cl(2) and the corresponding palladium(II) complexes 1-4, were prepared and characterized by IR, (1)H
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