SML0366

Cipamfylline

≥98% (HPLC)

• Synonym(s): 8-Amino-1,3-bis(cyclopropylmethyl)-3,9-dihydro-1H-Purine-2,6-dione, BRL 61063
• Empirical Formula (Hill Notation): C₁₃H₁₇N₅O₂
• CAS Number: 132210-43-6
• Molecular Weight: 275.31
• UNSPSC Code: 41106305
• PubChem Substance ID: 329825367
• NACRES: NA.77
• Assay: ≥98% (HPLC)
• Form: powder

Properties

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: >10 mg/mL
• storage temp.: 2-8°C
• SMILES string: Nc1nc2N(CC3CC3)C(=O)N(CC4CC4)C(=O)c2[nH]1
• InChI: 1S/C13H17N5O2/c14-12-15-9-10(16-12)17(5-7-1-2-7)13(20)18(11(9)19)6-8-3-4-8/h7-8H,1-6H2,(H3,14,15,16)
• InChI key: KSPYMJJKQMWWNB-UHFFFAOYSA-N

Description

Biochem/physiol Actions

Cipamfylline is a PDE4 inhibitor that has been shown to cause a cellular redistribution of PDE4A4 into accretion foci, through an association with the ubiquitin scaffolding protein p62.

Cipamfylline is a PDE4 inhibitor.

Features and Benefits

This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the Phosphodiesterases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable