A stable, cell-permeable, non-competitive adenylyl cyclase inhibitor that targets the P-site domain.
A stable, cell-permeable, non-competitive adenylyl cyclase inhibitor that targets the P-site domain. IC50 = 100 μM in detergent-dispersed rat brain preparation.
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Frontiers in neuroscience, 14, 364-364 (2020-05-16)
Electrical synapses between neurons exhibit a high degree of plasticity, which makes critical contributions to neuronal communication. The GABAergic parvalbumin-expressing (PV+) neurons in the thalamic reticular nucleus (TRN) interact with each other through electrical and chemical synapses. Plasticity of electrical
Cyclic nucleotides like cAMP modulate cell function via PKA activation and ion channels.
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