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Merck
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Key Documents

14701C

SAFC

EX-CELL® Glycosylation Adjust (Gal +)

protein quality supplement

Pharma Manufacturing

Synonym(s):

N-linked glycosylation reagent

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About This Item

UNSPSC Code:
12352207
NACRES:
NA.75

Quality Level

form

liquid

quality

GMP
chemically defined

technique(s)

cell culture | mammalian: suitable

impurities

Sterility Tested, pH, Endotoxin, and Appearance

suitability

suitable for manufacturing use

storage temp.

2-8°C

General description

A protein quality supplement that targets glycosylation attributes, EX-CELL® Glycosylation Adjust (Gal+) allows users to easily and quickly achieve desired N-linked glycosylation by increasing the galactose site occupancy on the oligosaccharide to a higher level. Supplementation demonstrates 2- to 4-fold increases in G1F and G2F distributions when compared to processes without addition of the product. The product can be used with a broad range of cell lines, is scalable, and is regulatory friendly.
GMP concentrated solution. Intended as a cell culture supplement. Recommended titration starting point, % volume/volume.

Packaging

14701C-100ML
14701C-1000ML

Linkage

Submit the EX-CELL Glycosylation Adjust (Gal +) request form to get in touch with a SAFC representative.

Legal Information

EX-CELL is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

10 - Combustible liquids

WGK

WGK 3


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Articles

Our protein quality supplement, EX-CELL® Glycosylation Adjust (Gal+), provides customers with a novel chemically defined product which targets glycosylation attributes.

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The biosimilar market is expected to grow rapidly in the coming years, as many blockbuster monoclonal antibodies lose patent protection by 2020.

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