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Key Documents

Y0001304

Butyl methanesulfonate

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

NSC 36060

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About This Item

Empirical Formula (Hill Notation):
C5H12O3S
CAS Number:
Molecular Weight:
152.21
UNSPSC Code:
41116107
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

imatinib

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

InChI

1S/C5H12O3S/c1-3-4-5-8-9(2,6)7/h3-5H2,1-2H3

InChI key

LFLBHTZRLVHUQC-UHFFFAOYSA-N

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Butyl methanesulfonate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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R Saffhill
Carcinogenesis, 5(5), 621-625 (1984-05-01)
The reaction of N-n-butyl-N-nitrosourea ( BNU ) and n-butyl methanesulphonate (BMS) with DNA has been investigated. In addition to the expected n- butylpurines formed on reaction with BNU some rearranged sec-butyl-adducts were also observed, indicating that a carbonium ion is
J C Ball et al.
Environmental and molecular mutagenesis, 13(2), 100-106 (1989-01-01)
This report describes experiments in which a chiral alkyl methanesulfonate was used to investigate possible mechanisms by which alkylating agents cause their mutagenic, cytotoxic, and clastogenic effects. Optically active enantiomers and the racemic mixture of 2-butyl methanesulfonate (2-BMS) were cytotoxic
A R Rao
International journal of cancer, 28(1), 105-110 (1981-07-15)
The influence of pregnant mare serum gonadotropin (PSGM) on the induction of ovarian tumors by carcinogen(DMBA) and/or mutagens (EMS and BMS) has been studied in Swiss albino mice. Priming of the ovaries of 6-week-old mice with PMSG (50 IU/mouse) 24
H Hoppe et al.
Mutation research, 250(1-2), 411-421 (1991-09-11)
Cells of the human lymphoblast line WI-L2 and its derivative TK-6 were synchronized by centrifugal elutriation and cell-cycle dependent mutation to 6TGR (HPRT) and OUAR (Na+, K+ ATPase) measured. Bromodeoxyuridine induced 6TGR and OUAR mutations within S phase while butylmethyl-sulfonate

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