Skip to Content
Merck
All Photos(1)

Key Documents

66011

Sigma-Aldrich

Alcianblue 8GX solution

for microscopy, 1% in solution (in 3% acetic acid)

Sign Into View Organizational & Contract Pricing


About This Item

CAS Number:
MDL number:
UNSPSC Code:
12171500
PubChem Substance ID:
NACRES:
MA.02

grade

for microscopy

Quality Level

form

liquid

concentration

1% in solution (in 3% acetic acid)

density

0.996-1.016 g/cm3

ε (extinction coefficient)

2.4 at 619 nm in H2O

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

2-8°C
room temp

InChI

1S/C56H68N16S4.4ClH.Cu/c1-65(2)53(66(3)4)73-29-33-17-21-37-41(25-33)49-57-45(37)62-50-43-27-35(31-75-55(69(9)10)70(11)12)19-23-39(43)47(59-50)64-52-44-28-36(32-76-56(71(13)14)72(15)16)20-24-40(44)48(60-52)63-51-42-26-34(18-22-38(42)46(58-51)61-49)30-74-54(67(5)6)68(7)8;;;;;/h17-28H,29-32H2,1-16H3;4*1H;/q+2;;;;;+2/p-4

InChI key

CKLBXIYTBHXJEH-UHFFFAOYSA-J

General description

Alcian blue is a large conjugated dye molecule, and comprises of a central copper-containing pthalocyanine ring linked to four isothiouronium groups via thioether bonds. The isothiouronium groups are responsible for the cationic nature of alcian blue owing to them being moderately strong bases. It was initially used in dyeing of textile fibres. Alcian blue 8GX is a dye recommended normally for histological technique.

Application

Alcianblue 8GX solution has been used as a staining dye for chondrocytic, osteoblastic and adipocytic differentiation. It has also been used for the staining of sections in immunohistochemistry.

Analysis Note

1% solution in 3% acetic acid

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

John D. Bancroft
Theory and Practice of Histological Techniques, 172-172 (2008)
Oxygen tension regulates chondrocyte differentiation and function during endochondral ossification.
Hirao M et al.
The Journal of Biological Chemistry, 281, 31079-31079 (2006)
Yong Mao et al.
Acta biomaterialia, 85, 75-83 (2018-12-12)
A significant expansion of autologous chondrocytes in vitro is required for cell-based cartilage repair. However, the in vitro expansion of chondrocytes under standard culture conditions inevitably leads to the dedifferentiation of chondrocytes and contributes to suboptimal clinical outcomes. To address
Aurora-a is essential for the tumorigenic capacity and chemoresistance of colorectal cancer stem cells.
Cammareri P et al.
Cancer Research, 70, 4655-4655 (2010)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service