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Supelco

Aflatoxin G1

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About This Item

Empirical Formula (Hill Notation):
C17H12O7
CAS Number:
Molecular Weight:
328.27
Beilstein:
1299768
EC Number:
MDL number:
UNSPSC Code:
85151701
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard
reference material

shelf life

limited shelf life, expiry date on the label

manufacturer/tradename

Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

neat

storage temp.

−20°C

SMILES string

COc1cc2OC3OC=CC3c2c4OC(=O)C5=C(CCOC5=O)c14

InChI

1S/C17H12O7/c1-20-9-6-10-12(8-3-5-22-17(8)23-10)14-11(9)7-2-4-21-15(18)13(7)16(19)24-14/h3,5-6,8,17H,2,4H2,1H3

InChI key

XWIYFDMXXLINPU-UHFFFAOYSA-N

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General description

Aflatoxins are mycotoxins that are generated as a result of secondary metabolism of various fungal species such as Aspergillus, Penicillium and Fusarium.

Application

Aflatoxin G1 may be used as an analytical reference standard for the determination of aflatoxin G1 in:
  • Animal feed by high performance liquid chromatography with fluorescence detection (HPLC-FLD), as well as quick, easy, cheap, effective, rugged and safe (QuEChERS) extraction method combined with ultra-high performance liquid chromatography-high resolution mass spectrometry (UHPLC-HRMS).
  • Eggs by QuEChERS extraction method followed by analysis using UHPLC with tandem mass spectrometry (MS/MS) operating on electrospray ionization interface (ESI) mode.
  • Brazil nuts by immunoaffinity column (IAC) clean-up and HPLC-FLD
  • Plant-based milk and dairy products by dispersive liquid-liquid microextraction (DLLME), QuEChERS extraction method and HPLC-FLD.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Warning

Possibly carcinogenic.

Pictograms

Skull and crossbonesHealth hazard

Signal Word

Danger

Hazard Classifications

Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Carc. 1B - Muta. 1B

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number

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Extended validation of a sensitive and robust method for simultaneous quantification of aflatoxins B1, B2, G1 and G2 in Brazil nuts by HPLC-FLD.
Campos WEO, et al.
J. Food Compos. Anal., 60(10), 90-96 (2017)
Target analysis and retrospective screening of veterinary drugs, ergot alkaloids, plant toxins and other undesirable substances in feed using liquid chromatography-high resolution mass spectrometry.
Leon N, et al.
Talanta, 149(1), 43-52 (2016)
Rapid and automated analysis of aflatoxin M1 in milk and dairy products by online solid phase extraction coupled to ultra-high-pressure-liquid-chromatography tandem mass spectrometry.
Campone L, et al.
Journal of Chromatography A, 1428, 212-219 (2016)
Analytical method development and monitoring of Aflatoxin B1, B2, G1, G2 and Ochratoxin A in animal feed using HPLC with Fluorescence detector and photochemical reaction device.
Kim HJ, et al.
Cogent Food & Agriculture, 3(1), 1419788-1419788 (2017)
Hongmei Zeng et al.
Applied microbiology and biotechnology, 90(2), 635-650 (2010-12-15)
In aflatoxin biosynthesis, aflatoxins G(1) (AFG(1)) and B(1) (AFB(1)) are independently produced from a common precursor, O-methylsterigmatocystin (OMST). Recently, 11-hydroxy-O-methylsterigmatocystin (HOMST) was suggested to be a later precursor involved in the conversion of OMST to AFB(1), and conversion of HOMST

Protocols

LC/MS/MS Analysis of Aflatoxins in Hops on Ascentis® Express 2.7 μm Phenyl-Hexyl after Cleanup Using Supel™ Tox AflaZea SPE

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