QBD10193
Biotin-dPEG®3-NH3+TFA-
>95% (HPLC)
Synonym(s):
Biotin-PEG-Amine, Biotin-PEG3-NH3-TFA-, Biotin-PEG3-amine TFA salt, Biotin-PEG3-ammonium trifluoroacetate
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About This Item
Assay
>95% (HPLC)
form
solid or viscous liquid
reaction suitability
reaction type: Biotinylations
reaction type: Pegylations
polymer architecture
shape: linear
functionality: monofunctional
shipped in
ambient
storage temp.
−20°C
Features and Benefits
Biotin-dPEG3-NH3+TFA- (Biotin-dPEG3-ammonium trifluoroacetate) reacts with activated esters (N-hydroxysuccinimide, 2,3,5,6-tetrafluorophenyl) of carboxylic acids under mildly basic conditions. It can be coupled directly to a carboxylic acid using 1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC) chemistry. Also, the product can react with carbonyl groups (aldehydes or ketones) to form a Schiff base. The Schiff base can be reduced to a secondary amine using sodium cyanoborohydride if additional conjugate stability is necessary. Biotin-dPEG3-NH3+TFA- can be used to biotinylate antibodies useful in western blotting and immunohistochemical applications.
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Automate your Biotin tagging with Synple Automated Synthesis Platform (SYNPLE-SC002)
Legal Information
Products Protected under U.S. Patent #s 7,888,536 & 8,637,711 and European Patent #s 1,594,440 & 2,750,681
dPEG is a registered trademark of Quanta BioDesign
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
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