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E45309

Sigma-Aldrich

Ethyl phenylpropiolate

98%

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About This Item

Linear Formula:
C6H5C≡CCOOC2H5
CAS Number:
2216-94-6
Molecular Weight:
174.20
Beilstein:
639637
EC Number:
218-703-8
MDL number:
MFCD00009185
UNSPSC Code:
12352100
PubChem Substance ID:
24894561
NACRES:
NA.22

Assay

98%

form

liquid

refractive index

n20/D 1.552 (lit.)

bp

260-270 °C (lit.)

density

1.055 g/mL at 25 °C (lit.)

storage temp.

2-8°C

SMILES string

CCOC(=O)C#Cc1ccccc1

InChI

1S/C11H10O2/c1-2-13-11(12)9-8-10-6-4-3-5-7-10/h3-7H,2H2,1H3

InChI key

ACJOYTKWHPEIHW-UHFFFAOYSA-N

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Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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B H Shearer et al.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 23(4), 149-155 (1994-04-01)
The effects of four different hyperplastic agents and of the carcinogen DMBA on cytokeratin expression in hamster cheek pouch epithelia were compared. Reversible hyperplasia was produced by the application of either oil of turpentine, vitamin A or TPA. No hyperplastic
S K Gilmour et al.
Carcinogenesis, 13(1), 51-56 (1992-01-01)
Single applications of 12-O-tetradecanoylphorbol-13-acetate (TPA), mezerein or ethyl phenylpropriolate (EPP) to mouse skin at appropriate doses cause similar degrees of hyperplasia and comparable levels of induction of epidermal ornithine decarboxylase (ODC) activity. Multiple (n = 5) treatments with these agents
E Patrick et al.
Toxicology and applied pharmacology, 81(3 Pt 1), 476-490 (1985-12-01)
The possibility that chemicals induce skin irritation by multiple mechanisms was studied in laboratory mice. The time course and dose response to topical application of phenol, croton oil, benzalkonium chloride, ethyl phenylpropiolate (EPP), and methyl salicylate were compared. The responses
C S Baxter et al.
Carcinogenesis, 10(10), 1855-1861 (1989-10-01)
Responses of various cells of the epidermis and dermis to topically applied agents have been implicated in the mechanism of multistage mouse tumorigenesis. These responses have been discussed almost entirely in the context of a single promoter treatment, although tumor
G S Cameron et al.
The Journal of investigative dermatology, 99(2), 189-192 (1992-08-01)
The dorsal skin of hairless mice (Skh:HR-1) was treated with multiple applications of acetone, 12-O-tetradecanoyl-phorbol-13-acetate (TPA) or ethyl phenylpropionate (EPP) two times per week, or exposed to ultraviolet radiation (UVR) three times per week for treatment periods up to 16
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