42867
Dextran sulfate sodium salt
Mr ~40,000
Synonym(s):
DSS Dextran Sulfate Sodium
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About This Item
UNSPSC Code:
12352201
NACRES:
NA.25
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form
powder
mol wt
Mr ~40,000
loss
≤10% loss on drying
color
white to off-white
useful pH range
6.0-8 (10 g/L)
mp
(Decomposes on heating.)
solubility
water: soluble
storage temp.
room temp
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General description
Dextran is a polymer of anhydroglucose. It is composed of approximately 95% alpha-D-(166) linkages. The remaining (163) linkages account for the branching of dextran.
Application
Dextran sulfate is routinely used for the selective precipitation of lipoproteins, probe hybridization membrane-immobilized DNA, the release of DNA from DNA-histone complexes, and the inhibition of RNA binding to ribosomes.
Biochem/physiol Actions
Treatment with dextran sulfate sodium triggers development of colitis in mice and rats by binding to medium-chain-length fatty acids present in the colon and inducing inflammation.
Other Notes
To gain a comprehensive understanding of our extensive range of Dextrans for your research, we encourage you to visit our Carbohydrates Category page.
Storage Class Code
11 - Combustible Solids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
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